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肺高血圧ラットにおいて、経口エンドセリン受容体拮抗薬と経口プロスタサイクリン製剤との併用療法は各薬剤の単独療法より有効である
http://hdl.handle.net/2241/6099
http://hdl.handle.net/2241/60997ff063cc-4c5f-4a0b-a0d6-ccbb3855efc2
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Item type | Thesis or Dissertation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-07-25 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Combination of oral endothelin-A receptor antagonist and oral prostacyclin analogue is superior to each drug alone in ameliorating pulmonary hypertension in rats | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 肺高血圧ラットにおいて、経口エンドセリン受容体拮抗薬と経口プロスタサイクリン製剤との併用療法は各薬剤の単独療法より有効である | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||
タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
上野, 倫彦
× 上野, 倫彦 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Pulmonary hypertension (PH) is a poor prognostic and drug-resistant disease. Recently, it has been reported that continuous intravenous prostacyclin (PGI2) administration is effectual for PH; however, its effect is not sufficient to treat PH. We previously reported that chronic treatment with an endothelin (ET)-A receptor antagonist was effective for PH in rats. In this study, we investigated whether the combination on an oral ET-A receptor antagonist and an oral PGI2 analogue is superior to the single use of each drug alone for treating PH. Methods and Results ... | |||||
言語 | en | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Includes bibliographical references | |||||
言語 | en | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Includes supplementary treatises | |||||
言語 | en | |||||
書誌情報 |
発行日 2001 |
|||||
取得学位 | ||||||
学位名 | 博士(医学) | |||||
取得学位 | ||||||
学位名 | Doctor of Philosophy in Medical Sciences | |||||
学位授与大学 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 12102 | |||||
言語 | ja | |||||
学位授与機関名 | 筑波大学 | |||||
言語 | en | |||||
学位授与機関名 | University of Tsukuba | |||||
学位授与年度 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 2000 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2001-03-23 | |||||
報告番号 | ||||||
学位授与番号 | 甲第2663号 |