@phdthesis{oai:tsukuba.repo.nii.ac.jp:00008943, author = {上野, 倫彦 and Ueno, Michihiko}, month = {}, note = {Pulmonary hypertension (PH) is a poor prognostic and drug-resistant disease. Recently, it has been reported that continuous intravenous prostacyclin (PGI2) administration is effectual for PH; however, its effect is not sufficient to treat PH. We previously reported that chronic treatment with an endothelin (ET)-A receptor antagonist was effective for PH in rats. In this study, we investigated whether the combination on an oral ET-A receptor antagonist and an oral PGI2 analogue is superior to the single use of each drug alone for treating PH. Methods and Results ..., 2000, Includes bibliographical references, Includes supplementary treatises}, school = {筑波大学, University of Tsukuba}, title = {Combination of oral endothelin-A receptor antagonist and oral prostacyclin analogue is superior to each drug alone in ameliorating pulmonary hypertension in rats}, year = {2001} }