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Preparation of monodisperse aqueous microspheres containing high concentration of l-ascorbic acid by microchannel emulsification
http://hdl.handle.net/2241/00128939
http://hdl.handle.net/2241/00128939dfdf8551-e048-4f86-80a7-d5c4535e73eb
名前 / ファイル | ライセンス | アクション |
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JM_32-6 (793.4 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2015-10-21 | |||||
タイトル | ||||||
タイトル | Preparation of monodisperse aqueous microspheres containing high concentration of l-ascorbic acid by microchannel emulsification | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Khalid, Nauman
× Khalid, Nauman× Kobayashi, Isao× Neves, Marcos A.× Uemura, Kunihiko× Nakajima, Mitsutoshi× Nabetani, Hiroshi |
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著者別名 |
中嶋, 光敏
× 中嶋, 光敏 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Monodisperse aqueous microspheres containing high concentrations of l-ascorbic acid with different concentrations of sodium alginate (Na-ALG) and magnesium sulfate (MgSO4) were prepared by using microchannel emulsification (MCE). The continuous phase was water-saturated decane containing a 5% (w/w) hydrophobic emulsifier. The flow rate of the continuous phase was maintained at 10 mL h−1, whereas the pressure applied to the disperse phase was varied between 3 and 25 kPa. The disperse phase optimized for successfully generating aqueous microspheres included 2% (w/w) Na-ALG and 1% (w/w) MgSO4. At a higher MgSO4 concentration, the generated microspheres resulted in coalescence and subsequent bursting. At a lower MgSO4 concentration, unstable and polydisperse microspheres were obtained. The aqueous microspheres generated from the MCs under optimized conditions had a mean particle diameter (dav) of 14–16 µm and a coefficient of variation (CV) of less than 8% at the disperse phase pressures of 5–15 kPa. | |||||
書誌情報 |
Journal of microencapsulation 巻 32, 号 6, p. 570-577, 発行日 2015-07 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0265-2048 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10641641 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 26190217 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3109/02652048.2015.1065919 | |||||
権利 | ||||||
権利情報 | This is an Accepted Manuscript of an article published by Taylor & Francis Group in Journal of Microencapsulation on 20 Jul 2015, available online: http://www.tandfonline.com/doi/abs/10.3109/02652048.2015.1065919. | |||||
著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | Taylor & Francis |