{"_buckets": {"deposit": "c4a2e6cb-eae7-486b-9898-5b9df8133e89"}, "_deposit": {"id": "9113", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "9113"}, "status": "published"}, "_oai": {"id": "oai:tsukuba.repo.nii.ac.jp:00009113"}, "item_12_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1993", "bibliographicIssueDateType": "Issued"}, "bibliographic_titles": [{}]}]}, "item_12_creator_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u5927\u897f\u3001\u6df3\u4e4b"}], "nameIdentifiers": [{"nameIdentifier": "36891", "nameIdentifierScheme": "WEKO"}]}]}, "item_12_description_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_12_description_33": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_description": "text", "subitem_description_type": "Other"}]}, "item_12_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "The renin-angiotensin system plays an important role in regulating blood pressure and electrolyte homeostasis (1-3). It operates through formation of the biologically activ octapeptide, angiotensin II (Ang II ) via sequential cleavage of circulating angiotensinogen and angiotensin I by renal renin and angiotensin-converting enzyme, respectively. Recently, numerous evidences have been accumulated suggesting that local renin-angiotensin systems exist in several oragans including the brain, adrenal, kidney, arterial walls, testis, and ovary (4), and research is in progress to outline their function. Ang II is through to generate the variety of effects through interaction with a cell surface specific receptor that subsequently transduces its signal into the appropriate cellular response. The existence of Ang II receptor subtypes has been suggested based on deiffrences in their physiological and biochemical characteristics (5-7). For example, Douglas (6) classified two types of Ang II receptor in rate renal cortex according to differences in affinity for Ang II and Ang III, the nature of receptor regulation and mechanisms of signal transduction. Gunther (7), on the other hand, described two subtypes of Ang II receptor in rat liver on deifferential \uff65\uff65\uff65", "subitem_description_type": "Abstract"}]}, "item_12_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "Thesis (Ph.D.)--University of Tsukuba, (A), no. 1160, 1993.3.25", "subitem_description_type": "Other"}]}, "item_12_identifier_34": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2241/6169"}]}, "item_12_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_12_subject_16": {"attribute_name": "\u65e5\u672c\u5341\u9032\u5206\u985e\u6cd5", "attribute_value_mlt": [{"subitem_subject": "491.32", "subitem_subject_scheme": "NDC"}]}, "item_12_subject_20": {"attribute_name": "NII\u30b5\u30d6\u30b8\u30a7\u30af\u30c8", "attribute_value_mlt": [{"subitem_subject": "\u57fa\u790e\u533b\u5b66", "subitem_subject_scheme": "Other"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ohnishi, Junji"}], "nameIdentifiers": [{"nameIdentifier": "36890", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2013-12-18"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "A1160.pdf", "filesize": [{"value": "336.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 336900.0, "url": {"label": "A1160.pdf", "url": "https://tsukuba.repo.nii.ac.jp/record/9113/files/A1160.pdf"}, "version_id": "984b9789-485e-4b58-90bf-a65739ae61d9"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "Characterization of angiotensin II receptor subtype", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Characterization of angiotensin II receptor subtype"}]}, "item_type_id": "12", "owner": "1", "path": ["3/233/243"], "permalink_uri": "http://hdl.handle.net/2241/6169", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2007-07-25"}, "publish_date": "2007-07-25", "publish_status": "0", "recid": "9113", "relation": {}, "relation_version_is_last": true, "title": ["Characterization of angiotensin II receptor subtype"], "weko_shared_id": null}