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Angiographic Findings in Patients with Hepatocellular Carcinoma Previously Treated Using Proton Beam Therapy
http://hdl.handle.net/2241/00159302
http://hdl.handle.net/2241/001593029292b153-9e54-4181-8764-a13ba62fc96e
名前 / ファイル | ライセンス | アクション |
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JO_2019-3580379 (3.1 MB)
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Item type | Journal Article(1) | |||||||||||
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公開日 | 2020-01-14 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | Angiographic Findings in Patients with Hepatocellular Carcinoma Previously Treated Using Proton Beam Therapy | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
資源タイプ | ||||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
タイプ | journal article | |||||||||||
著者 |
森, 健作
× 森, 健作× 奥村, 敏之
WEKO
204107
× 櫻井, 英幸× Takahashi, Hiroaki× Sekino, Yuta× Hiyama, Takashi× Fukuda, Kuniaki× Hasegawa, Naoyuki× Sakai, Masafumi× Kikuchi, Shunsuke× Takei, Yohei× Iizumi, Takashi× Minami, Manabu |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Given the growing interest in using proton beam therapy (PBT) for hepatocellular carcinoma (HCC), it is possible that transarterial chemoembolization (TACE) could be used for selected patients who have previously undergone PBT. However, these cases can be technically challenging to treat and require appropriate preparation. Thus, we aimed to identify angiographic findings in this setting. We retrospectively identified 31 patients (28 men and 3 women, mean age: 69 years, range: 43–84 years) who underwent hepatic angiography plus TACE or transarterial infusion chemotherapy (TAI) for HCC that recurred after PBT (July 2007 to June 2018). We discovered four angiographic findings, which we speculate were related to the previous PBT. 18 patients experienced recurrence in the irradiated field, and 13 patients experienced recurrence outside the irradiated field. 29 patients underwent TACE and only 2 patients underwent TAI. The mean number of previous PBT treatments was 1.3 ± 0.6 (range: 1–4). The median interval from the earliest PBT treatment to hepatic angiography was 559 days (range: 34–5,383 days), and the median interval from the latest PBT treatment to hepatic angiography was 464 days (range: 34–5,383 days). Abnormal staining of the irradiated liver parenchyma was observed in 22 patients, which obscured the angiographic tumor staining in 4 patients. Development of a tortuous tumor feeder vessel was observed in 13 patients. Development of an extrahepatic collateral pathway was observed in 7 patients. Development of an arterioportal or arteriovenous shunt was observed in 4 patients. Based on these findings, we conclude that PBT was associated with various angiographic findings during subsequent transarterial chemotherapy for recurrent HCC, and familiarity with these findings will be important in developing appropriate treatment plans. | |||||||||||
書誌情報 |
en : Journal of Oncology 巻 2019, p. 3580379, 発行日 2019-07 |
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ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1687-8450 | |||||||||||
PubMed番号 | ||||||||||||
識別子タイプ | PMID | |||||||||||
関連識別子 | 31354819 | |||||||||||
DOI | ||||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | 10.1155/2019/3580379 | |||||||||||
権利 | ||||||||||||
権利情報 | © 2019 Hiroaki Takahashi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||||||||
著者版フラグ | ||||||||||||
値 | publisher | |||||||||||
出版者 | ||||||||||||
出版者 | Hindawi |