WEKO3
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Preliminary in vivo magnetofection data using magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals
http://hdl.handle.net/2241/00154118
http://hdl.handle.net/2241/0015411864a24d6a-1c13-4cca-b718-518f9f2aeb06
名前 / ファイル | ライセンス | アクション |
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DB_18-1696 (1.1 MB)
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Item type | Journal Article(1) | |||||||||||
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公開日 | 2019-01-18 | |||||||||||
タイトル | ||||||||||||
タイトル | Preliminary in vivo magnetofection data using magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
資源タイプ | ||||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
タイプ | journal article | |||||||||||
著者 |
プエンテス, サンドラ
× プエンテス, サンドラ
WEKO
204740
× Shubhra, Quazi T.H.× Oyane, Ayako× Nakamura, Maki× Marushima, Aiki× Tsurushima, Hideo |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | The data reported herein are in association with our research article entitled "Rapid one-pot fabrication of magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals using injection solutions for magnetofection and magnetic targeting" (Shubhra et al. 2017) [1]. This article reports morphological and gene delivery (in vitro and preliminary in vivo) data of those calcium phosphate (CaP) naonparticles (NPs) with various iron oxide (IO) contents, named as CaP-Fe(1), CaP-Fe(2), CaP-Fe(3), CaP-Fe(4), and CaP-Fe(5), which were prepared via coprecipitation in supersaturated CaP solutions with nominal Fe concentrations 6.97, 13.94, 27.87, 55.74, and 139.35 μg/mL, respectively. Morphological data of four different NPs: CaP-Fe(1), CaP-Fe(2), CaP-Fe(4), and CaP-Fe(5) are shown here. Data of the luciferase reporter gene expression assay show the effects of the coprecipitation time and the dosage of the CaP-Fe(3) NPs on gene expression levels of CHO-K1 cells transfected by the NPs without external magnetic field. It is demonstrated using digital and microscopic images that the CaP-Fe(3) NPs localize near the periphery of the external magnet that was placed under the cell culture plate. Using the CaP-Fe(3) NPs, animal experiments were conducted to obtain preliminary in vivo magnetofection data. | |||||||||||
書誌情報 |
Data in Brief 巻 18, p. 1696-1701, 発行日 2018-04 |
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ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 23523409 | |||||||||||
PubMed番号 | ||||||||||||
識別子タイプ | PMID | |||||||||||
関連識別子 | 29904669 | |||||||||||
DOI | ||||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | 10.1016/j.dib.2018.04.058 | |||||||||||
権利 | ||||||||||||
権利情報 | ©2018TheAuthors. | |||||||||||
権利 | ||||||||||||
権利情報 | Published by ElsevierInc.This is an open access article under the CCBY license. | |||||||||||
著者版フラグ | ||||||||||||
値 | publisher | |||||||||||
出版者 | ||||||||||||
出版者 | Elsevier |