{"_buckets": {"deposit": "cadd1dd3-f356-49a9-b7ea-e84df124572c"}, "_deposit": {"created_by": 25, "id": "2001688", "owner": "25", "owners": [25], "owners_ext": {"displayname": "wataka", "username": "kuma1008"}, "pid": {"revision_id": 0, "type": "depid", "value": "2001688"}, "status": "published"}, "_oai": {"id": "oai:tsukuba.repo.nii.ac.jp:02001688", "sets": ["2206", "1635225066520"]}, "author_link": ["695"], "item_5_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2020-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "516", "bibliographicPageStart": "507", "bibliographicVolumeNumber": "16", "bibliographic_titles": [{"bibliographic_title": "Future Oncology", "bibliographic_titleLang": "en"}]}]}, "item_5_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background: Nonmuscle-invasive bladder cancer (NMIBC) is the most common form of bladder cancer, with high rates of disease recurrence and progression. Current treatment for high-risk NMIBC involves Bacillus Calmette-Guérin (BCG) therapy, but treatment options are limited for patients with recurrent or BCG-unresponsive disease. Aberrant programmed death 1 signaling has been implicated in BCG resistance and bladder cancer recurrence and progression, and pembrolizumab has shown efficacy in patients with BCG-unresponsive high-risk NMIBC. Aim: To describe the rationale and design for the randomized, comparator-controlled Phase III KEYNOTE-676 study, which will evaluate the efficacy and safety of pembrolizumab in combination with BCG in patients with persistent/recurrent high-risk NMIBC after BCG induction therapy.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_5_publisher_27": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Future Medicine", "subitem_publisher_language": "en"}]}, "item_5_relation_10": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "32162533", "subitem_relation_type_select": "PMID"}}]}, "item_5_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.2217/fon-2019-0817", "subitem_relation_type_select": "DOI"}}]}, "item_5_relation_9": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.2217/fon-2019-0817", "subitem_relation_type_select": "DOI"}}]}, "item_5_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/", "subitem_rights_language": "en"}]}, "item_5_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_5_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1479-6694", "subitem_source_identifier_type": "PISSN"}]}, "item_5_source_id_9": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA1206226X", "subitem_source_identifier_type": "NCID"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kamat, Ashish M", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Shore, Neal", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hahn, Noah", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Alanee, Shaheen", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "西山, 博之", "creatorNameLang": "ja"}, {"creatorName": "ニシヤマ, ヒロユキ", "creatorNameLang": "ja-Kana"}, {"creatorName": "NISHIYAMA, Hiroyuki", "creatorNameLang": "en"}], "familyNames": [{"familyName": "西山", "familyNameLang": "ja"}, {"familyName": "ニシヤマ", "familyNameLang": "ja-Kana"}, {"familyName": "NISHIYAMA", "familyNameLang": "en"}], "givenNames": [{"givenName": "博之", "givenNameLang": "ja"}, {"givenName": "ヒロユキ", "givenNameLang": "ja-Kana"}, {"givenName": "Hiroyuki", "givenNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "695", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "20324642", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://nrid.nii.ac.jp/ja/nrid/1000020324642"}, {"nameIdentifier": "0000003058", "nameIdentifierScheme": "筑波大学研究者総覧", "nameIdentifierURI": "http://trios.tsukuba.ac.jp/researcher/0000003058"}]}, {"creatorNames": [{"creatorName": "Shariat, Shahrokh", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nam, Kijoeng", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kapadia, Ekta", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Frenkl, Tara", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Steinberg, Gary", "creatorNameLang": "en"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "date": [{"dateType": "Available", "dateValue": "2021-10-26"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "FO_16-10.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_5", "mimetype": "application/pdf", "size": 1500000.0, "url": {"objectType": "fulltext", "url": "https://tsukuba.repo.nii.ac.jp/record/2001688/files/FO_16-10.pdf"}, "version_id": "3d21e617-54bd-4146-9726-5b155d1267b9"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "KEYNOTE-676: Phase III study of BCG and pembrolizumab for persistent/recurrent high-risk NMIBC", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "KEYNOTE-676: Phase III study of BCG and pembrolizumab for persistent/recurrent high-risk NMIBC", "subitem_title_language": "en"}]}, "item_type_id": "5", "owner": "25", "path": ["2206", "1635225066520"], "permalink_uri": "http://hdl.handle.net/2241/0002001688", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-10-26"}, "publish_date": "2021-10-26", "publish_status": "0", "recid": "2001688", "relation": {}, "relation_version_is_last": true, "title": ["KEYNOTE-676: Phase III study of BCG and pembrolizumab for persistent/recurrent high-risk NMIBC"], "weko_shared_id": -1}
KEYNOTE-676: Phase III study of BCG and pembrolizumab for persistent/recurrent high-risk NMIBC
http://hdl.handle.net/2241/0002001688
http://hdl.handle.net/2241/0002001688