WEKO3
アイテム
{"_buckets": {"deposit": "35e61cf9-d863-4f5d-b712-ec25bac53388"}, "_deposit": {"id": "17590", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "17590"}, "status": "published"}, "_oai": {"id": "oai:tsukuba.repo.nii.ac.jp:00017590", "sets": []}, "author_link": ["117", "62488", "62489", "62490", "62491", "62492", "62493", "62494", "62495", "62496", "62497"], "control_number": "17590", "item_1644910766877": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_5_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1996-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "581", "bibliographicPageStart": "573", "bibliographicVolumeNumber": "4", "bibliographic_titles": [{"bibliographic_title": "Immunity", "bibliographic_titleLang": "en"}]}]}, "item_5_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Intercellular adhesion molecules play an important role in the generation of T lymphocytemediated immune responses. Here, we describe a novel accessory molecule, DNAX accessory molecule-1 (DNAM-1), that is constitutively expressed on the majority of peripheral blood T lymphocytes. DNAM-1 is a 65 kDa transmembrane glycoprotein consisting of 318 aa includ- ing two immunoglobulin-like domains. Anti-DNAM-1 monoclonal antibody (MAb) inhibits T and NK cellmediated cytotoxicity against a variety of tumor cell targets and blocks cytokine production by alloanti- gen-specific T cells. In addition, DNAM-1 is a tyrosine-phosphorylated signal-transducing molecule that participates in primary adhesion during cytotoxic T lymphocyte (CTL)mediated cytotoxicity.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_5_identifier_34": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2241/102273"}]}, "item_5_publisher_27": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier (Cell Press)", "subitem_publisher_language": "fr"}]}, "item_5_relation_10": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "8673704", "subitem_relation_type_select": "PMID"}}]}, "item_5_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/S1074-7613(00)70060-4", "subitem_relation_type_select": "DOI"}}]}, "item_5_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 1996 Cell Press", "subitem_rights_language": "en"}]}, "item_5_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1074-7613", "subitem_source_identifier_type": "PISSN"}]}, "item_5_source_id_9": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11006671", "subitem_source_identifier_type": "NCID"}]}, "item_5_subject_20": {"attribute_name": "NIIサブジェクト", "attribute_value_mlt": [{"subitem_subject": "医学", "subitem_subject_scheme": "Other"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shibuya, Akira", "creatorNameLang": "en"}, {"creatorName": "渋谷, 彰", "creatorNameLang": "ja"}], "nameIdentifiers": [{"nameIdentifier": "117", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "80216027", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://nrid.nii.ac.jp/ja/nrid/1000080216027"}, {"nameIdentifier": "0000001643", "nameIdentifierScheme": "筑波大学研究者総覧", "nameIdentifierURI": "http://trios.tsukuba.ac.jp/researcher/0000001643"}]}, {"creatorNames": [{"creatorName": "Campbell, David", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62488", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hannum, Charles", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62489", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yssel, Hans", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62490", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Franz-Bacon, Karin", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62491", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Terrill, McClanahan", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62492", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitamura, Toshio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62493", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nicholl, Jillian", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62494", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sutherland, Grant R", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62495", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Lanie, Lewis L", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62496", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Phillips, Joseph H", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "62497", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2013-12-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Immunity_4-6.pdf", "filesize": [{"value": "87.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 87800.0, "url": {"label": "Immunity_4-6.pdf", "objectType": "fulltext", "url": "https://tsukuba.repo.nii.ac.jp/record/17590/files/Immunity_4-6.pdf"}, "version_id": "29491522-2dbb-4348-83a2-1c7813a8bc9c"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes", "subitem_title_language": "en"}]}, "item_type_id": "5", "owner": "1", "path": ["604", "543"], "permalink_uri": "http://hdl.handle.net/2241/102273", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2009-04-15"}, "publish_date": "2009-04-15", "publish_status": "0", "recid": "17590", "relation": {}, "relation_version_is_last": true, "title": ["DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes"], "weko_shared_id": 5}
DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes
http://hdl.handle.net/2241/102273
http://hdl.handle.net/2241/10227399e7bd2e-6c60-4075-a758-31d03fd0203c
名前 / ファイル | ライセンス | アクション |
---|---|---|
Immunity_4-6.pdf (87.8 kB)
|
|
Item type | Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2009-04-15 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
渋谷, 彰
× 渋谷, 彰× Campbell, David× Hannum, Charles× Yssel, Hans× Franz-Bacon, Karin× Terrill, McClanahan× Kitamura, Toshio× Nicholl, Jillian× Sutherland, Grant R× Lanie, Lewis L× Phillips, Joseph H |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Intercellular adhesion molecules play an important role in the generation of T lymphocytemediated immune responses. Here, we describe a novel accessory molecule, DNAX accessory molecule-1 (DNAM-1), that is constitutively expressed on the majority of peripheral blood T lymphocytes. DNAM-1 is a 65 kDa transmembrane glycoprotein consisting of 318 aa includ- ing two immunoglobulin-like domains. Anti-DNAM-1 monoclonal antibody (MAb) inhibits T and NK cellmediated cytotoxicity against a variety of tumor cell targets and blocks cytokine production by alloanti- gen-specific T cells. In addition, DNAM-1 is a tyrosine-phosphorylated signal-transducing molecule that participates in primary adhesion during cytotoxic T lymphocyte (CTL)mediated cytotoxicity. | |||||
言語 | en | |||||
書誌情報 |
en : Immunity 巻 4, 号 6, p. 573-581, 発行日 1996-06 |
|||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1074-7613 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11006671 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 8673704 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/S1074-7613(00)70060-4 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 1996 Cell Press | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
出版者 | ||||||
言語 | fr | |||||
出版者 | Elsevier (Cell Press) | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2241/102273 | |||||
識別子タイプ | HDL |