{"created":"2021-03-01T06:44:28.973104+00:00","id":8978,"links":{},"metadata":{"_buckets":{"deposit":"dffa1fd5-545d-4b2e-82b1-f410bfcfe702"},"_deposit":{"created_by":221,"id":"8978","owners":[221],"pid":{"revision_id":0,"type":"depid","value":"8978"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00008978","sets":["3:233:239"]},"author_link":["36503"],"item_12_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003","bibliographicIssueDateType":"Issued"}}]},"item_12_date_granted_46":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2003-03-25"}]},"item_12_degree_grantor_44":{"attribute_name":"学位授与大学","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"筑波大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"University of Tsukuba"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"12102","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_12_degree_name_43":{"attribute_name":"取得学位","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"},{"subitem_degreename":"Doctor of Philosophy in Medical Sciences"}]},"item_12_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"目的：SREBPは、脂質合成に中心的な役割を持つ転写因子である。また脂質代謝と糖代謝・インスリン作用には密接な関連が推察される。PEPCK-SREBP-1a transgenic mouse（TgSREBP-1a）では肝脂質合成関連酵素が発現上昇し、著明な脂肪肝と脂肪組織萎縮という特徴的な表現型を持つ。SREBP-1の作用、臓器への脂肪蓄積およびインスリン感受性の相互関係解析の目的でTgSREBP-1aはよいモデルとなるため糖負荷試験を中心に検討した。 ...","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_12_description_45":{"attribute_name":"学位授与年度","attribute_value_mlt":[{"subitem_description":"2002","subitem_description_type":"Other"}]},"item_12_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"付: 参考文献","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_12_dissertation_number_47":{"attribute_name":"報告番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第3193号"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高橋, 昭光","creatorNameLang":"ja"},{"creatorName":"Takahashi, Akimitsu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"36503","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-12-18"}],"displaytype":"detail","filename":"A3193.pdf","filesize":[{"value":"130.8 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"abstract","url":"https://tsukuba.repo.nii.ac.jp/record/8978/files/A3193.pdf"},"version_id":"3cbf4f92-911f-4014-b593-cfdd53ac98b4"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-12-18"}],"displaytype":"detail","filename":"1.pdf","filesize":[{"value":"31.0 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"summary","url":"https://tsukuba.repo.nii.ac.jp/record/8978/files/1.pdf"},"version_id":"827c1b7c-85c2-4793-8b49-7188574d578b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"脂肪肝と脂肪萎縮を伴なうSREBP-1aトランスジェニックマウスにおける耐糖能およびインスリン抵抗性の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"脂肪肝と脂肪萎縮を伴なうSREBP-1aトランスジェニックマウスにおける耐糖能およびインスリン抵抗性の検討","subitem_title_language":"ja"}]},"item_type_id":"12","owner":"221","path":["239"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-07-25"},"publish_date":"2007-07-25","publish_status":"0","recid":"8978","relation_version_is_last":true,"title":["脂肪肝と脂肪萎縮を伴なうSREBP-1aトランスジェニックマウスにおける耐糖能およびインスリン抵抗性の検討"],"weko_creator_id":"221","weko_shared_id":-1},"updated":"2024-02-07T23:53:31.238852+00:00"}