@phdthesis{oai:tsukuba.repo.nii.ac.jp:00008597, author = {Hatsuzawa, Kiyotaka and 初沢, 清隆}, month = {}, note = {The great majority of peptide-hormones and neurotransmitters are initially synthesized in endocrine and neuronal cells as inactive higher molecular weight precursor proteins that must undergo proteolytic cleavage to form the final biologically active peptide. Typically, this cleavage occurs at the carboxyl side of pairs of basic amino acid residues (primarily -Lys-Arg- and -Arg-Arg-) within the regulated secretory pathway(1-3). ..., 1992}, school = {筑波大学, University of Tsukuba}, title = {Studies on furin, a mammalian homologue of the yeast Kex2 processing endopeptidase}, year = {1993} }