{"created":"2021-03-01T07:37:58.102289+00:00","id":56791,"links":{},"metadata":{"_buckets":{"deposit":"8eb65e9c-64cd-42bd-9073-7b1badbf8954"},"_deposit":{"id":"56791","owners":[],"pid":{"revision_id":0,"type":"depid","value":"56791"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00056791","sets":["2780:4866","2780:7568","3:62:5619:8311"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"158","bibliographicPageStart":"154","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"日本生物学的精神医学会誌"},{"bibliographic_title":"Japanese Journal of Biological Psychiatry","bibliographic_titleLang":"en"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"妊娠中のウイルス感染は，仔のASD 発症リスクを上昇させる。ウイルス感染時にTh17細胞が産生するインターロイキン（IL）-17A がASD 病態生理の責任分子であることが示唆されている。私たちはIL-17Aをマウス脳室内に直接投与し，ミクログリアへの影響を調査した。IL-17A に曝されたミクログリアは活性化し，帯状回皮質の脳室面に局在していた。本研究は，免疫分子IL-17A がASDの原因となる大脳皮質構造異常を引き起こすメカニズム理解の手がかりを与える。","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本生物学的精神医学会"}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.11249/jsbpjjpp.31.3_154","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"1.本誌に掲載する著作物の複製権・翻訳権・上映権・譲渡権・公衆送信権（送信可能化権を含む）は，日本生物学的精神医学会に譲渡されたものとします。    2.したがって，前項の諸権利の許諾は日本生物学的精神医学会が行います。なお，前項については，著者自身の使用を拘束するものではありません。"}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":" 2186-6465","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12468060","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐々木, 哲也"},{"creatorName":"ササキ, テツヤ","creatorNameLang":"ja-Kana"},{"creatorName":"SASAKI, Tetsuya","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"鮑, 培毅"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高田, 拓弥"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"武井, 陽介"},{"creatorName":"タケイ, ヨウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"TAKEI, Yosuke","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"BAO, Peiyi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKADA, Takuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-01-21"}],"displaytype":"detail","filename":"JJBP_31-154.pdf","filesize":[{"value":"772.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JJBP_31-154","url":"https://tsukuba.repo.nii.ac.jp/record/56791/files/JJBP_31-154.pdf"},"version_id":"ebff0af3-b8d4-4886-aa7b-0543ad61211b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"autism spectrum disorder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"CD68","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cerebral cortex","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-17A","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"microglia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"インターロイキン -17Aによる大脳皮質内ミクログリア活性化と局在への影響 : IL-17A による大脳皮質構築異常とASD発現機構の理解を目指して","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"インターロイキン -17Aによる大脳皮質内ミクログリア活性化と局在への影響 : IL-17A による大脳皮質構築異常とASD発現機構の理解を目指して"}]},"item_type_id":"5","owner":"1","path":["7568","4866","8311"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-01-21"},"publish_date":"2021-01-21","publish_status":"0","recid":"56791","relation_version_is_last":true,"title":["インターロイキン -17Aによる大脳皮質内ミクログリア活性化と局在への影響 : IL-17A による大脳皮質構築異常とASD発現機構の理解を目指して"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T09:27:35.469439+00:00"}