{"created":"2021-03-01T07:35:38.733054+00:00","id":54779,"links":{},"metadata":{"_buckets":{"deposit":"3c7e28e0-f3ea-45f1-8bf6-da516d6e3b0c"},"_deposit":{"id":"54779","owners":[],"pid":{"revision_id":0,"type":"depid","value":"54779"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00054779","sets":["160:523","2780:1760","3:62:5298:6470"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"2955","bibliographicPageStart":"2952","bibliographicVolumeNumber":"38","bibliographic_titles":[{},{"bibliographic_title":"Clinical Nutrition","bibliographic_titleLang":"en"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Olive leaf extracts are rich in several polyphenols having potential health benefits. We conducted the current parallel-group randomized controlled trial to compare the effects of long-term consumption of olive leaf tea (OLT) and green tea (GT) on hematological parameters in 31 female volunteers aged between 40 and 70 years of old. We found that RBC count, hemoglobin, and hematocrit were increased significantly in the OLT group than those of in the GT group at 6 and 12 weeks of intervention. Within-group comparison showed that hematocrit was significantly increased in the OLT group at 6 weeks of intervention, whereas RBC count and serum iron was significantly decreased in the GT group at 12 weeks of intervention. This is the first clinical study reporting the beneficial effects of continuous intake of OLT on hematological parameters. This observation is supported by our previous in vitro study reporting the differentiation-inducing effect of certain olive leaf components on human hematopoietic stem cells. However, further investigations in larger cohorts with a careful consideration of target population are required to confirm the preventive effect of OLT against anemia and other red cell disorders.","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"30501915","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.clnu.2018.11.009","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2018 The Author(s)."},{"subitem_rights":"This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)."}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"02615614","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10643818","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"橋本, 幸一"},{"creatorName":"ハシモト, コウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"HASHIMOTO, Koichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"礒田, 博子"},{"creatorName":"イソダ, ヒロコ","creatorNameLang":"ja-Kana"},{"creatorName":"ISODA, Hiroko","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Ferdousi, F.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Araki, R.","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-23"}],"displaytype":"detail","filename":"CN_38-6.pdf","filesize":[{"value":"486.9 kB"}],"format":"application/pdf","licensetype":"license_9","mimetype":"application/pdf","url":{"label":"CN_38-6","url":"https://tsukuba.repo.nii.ac.jp/record/54779/files/CN_38-6.pdf"},"version_id":"43b13349-1778-41de-aa73-864eb8f3e3ea"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Olive leaf tea may have hematological health benefit over green tea","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Olive leaf tea may have hematological health benefit over green tea","subitem_title_language":"en"}]},"item_type_id":"5","owner":"1","path":["523","1760","6470"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-06-23"},"publish_date":"2020-06-23","publish_status":"0","recid":"54779","relation_version_is_last":true,"title":["Olive leaf tea may have hematological health benefit over green tea"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T09:29:08.287153+00:00"}