{"created":"2021-03-01T07:32:58.836355+00:00","id":52416,"links":{},"metadata":{"_buckets":{"deposit":"95691804-cf79-4a76-8de0-90c5f5dc6de6"},"_deposit":{"id":"52416","owners":[],"pid":{"revision_id":0,"type":"depid","value":"52416"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00052416","sets":["160:852","3:62:5297:4936"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"154","bibliographicPageStart":"148","bibliographicVolumeNumber":"83","bibliographic_titles":[{"bibliographic_title":"Bioscience, biotechnology, and biochemistry"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aromatherapy uses plant essential oils and fragrant ingredients for relaxation, sleep assistance, and improvement of restlessness related to dementia. Certain aromatic substances increase the life span and stress tolerance of nematodes. We investigated effects of exposure to linalool, a linear chain monoterpenic alcohol that is present in the essential oils of many plants, and its optical isomer, l-linalool, in Caenorhabditis elegans. Nematodes were repelled by the odor of both linalool and l-linalool; however, linalool odor stimulation decreased fat accumulation and increased motility after thermal stress. Analysis of a gene-deficient mutant revealed that the DAF-16 insulin-signaling pathway, which is involved in heat stress tolerance, was enhanced by linalool treatment. Linalool stimulation increased the expression of downstream genes such as sod-3 and hsp-12.6 via DAF-16. We conclude that linalool odor induces a repelling behavior in nematodes, improves heat stress tolerance through the DAF-16 signaling pathway, and affects fat accumulation.","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"TAYLOR & FRANCIS"}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"30200822","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1080/09168451.2018.1518699","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is an Accepted Manuscript of an article published by Taylor & Francis in Bioscience, Biotechnology, and Biochemistry on Volume 83, Issue 1, 2019 available online: http://www.tandfonline.com/10.1080/09168451.2018.1518699."}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0916-8451","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10824164","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"坂本, 和一"},{"creatorName":"サカモト, カズイチ","creatorNameLang":"ja-Kana"},{"creatorName":"SAKAMOTO, Kazuichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Hirano, Naoko","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-10-03"}],"displaytype":"detail","filename":"BBB_83-1.pdf","filesize":[{"value":"500.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BBB_83-1","url":"https://tsukuba.repo.nii.ac.jp/record/52416/files/BBB_83-1.pdf"},"version_id":"f6ff7d76-c16b-4abc-91a6-b27830617978"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Linalool odor stimulation improves heat stress tolerance and decreases fat accumulation in nematodes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Linalool odor stimulation improves heat stress tolerance and decreases fat accumulation in nematodes"}]},"item_type_id":"5","owner":"1","path":["852","4936"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-10-03"},"publish_date":"2019-10-03","publish_status":"0","recid":"52416","relation_version_is_last":true,"title":["Linalool odor stimulation improves heat stress tolerance and decreases fat accumulation in nematodes"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T09:25:55.294953+00:00"}