{"created":"2021-03-01T07:32:11.618264+00:00","id":51726,"links":{},"metadata":{"_buckets":{"deposit":"b059d478-62bd-4959-82fb-1efff07bba5f"},"_deposit":{"id":"51726","owners":[],"pid":{"revision_id":0,"type":"depid","value":"51726"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00051726","sets":["2780:1488","2780:335","2780:5480","3:62:5592:1354"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"101","bibliographicPageStart":"98","bibliographicVolumeNumber":"328","bibliographic_titles":[{"bibliographic_title":"Journal of the neurological sciences"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The paramedian tract (PMT) neurons, a group of neurons associated with eye movement that project into the cerebellar flocculus, are present in or near the medial longitudinal fasciculus (MLF) in the paramedian region of the lower brainstem. A 66-year-old man with multiple sclerosis in whom downbeat nystagmus appeared along with right MLF syndrome due to a unilateral pontomedullary lesion is described. In light of these findings, a possible schema for the vestibular balance control mechanism circuit of the PMT neurons via the flocculus is presented. Damage to the PMT neurons impaired the elective inhibitory control mechanism of the anterior semicircular canal neural pathway by the flocculus. This resulted in the appearance of anterior semicircular canal-dominant vestibular imbalance and the formation of downbeat nystagmus.\n\nFrom the pathogenesis of this vertical vestibular nystagmus, the action of the PMT neurons in the vestibular eye movement neuronal pathway to maintain vestibular balance was conjectured to be as follows. PMT neurons transmit vestibular information from the anterior semicircular canals to the cerebellum, forming a cerebellum/brainstem feedback loop. Vestibular information from that loop is integrated in the cerebellum, inhibiting only the anterior semicircular canal neuronal pathway via the flocculus and controlling vestibular balance.","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier B.V."}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"23510567","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.jns.2013.02.017","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 Elsevier B.V."},{"subitem_rights":"NOTICE: this is the author’s version of a work that was accepted for publication in Journal of the neurological sciences. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of the neurological sciences, 328, 1-2, 2013, DOI: 10.1016/j.jns.2013.02.017"}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022510X","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00703265","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中馬越, 清隆"},{"creatorName":"ナカマゴエ, キヨタカ","creatorNameLang":"ja-Kana"},{"creatorName":"NAKAMAGOE, Kiyotaka","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"小金澤, 禎史"},{"creatorName":"コガネザワ, タダチカ","creatorNameLang":"ja-Kana"},{"creatorName":"KOGANEZAWA, Tadachika","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"玉岡, 晃"},{"creatorName":"タマオカ, アキラ","creatorNameLang":"ja-Kana"},{"creatorName":"TAMAOKA, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Fujizuka, Natsu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Tetsuto","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-19"}],"displaytype":"detail","filename":"JNS_328-1-2.pdf","filesize":[{"value":"971.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JNS_328-1-2","url":"https://tsukuba.repo.nii.ac.jp/record/51726/files/JNS_328-1-2.pdf"},"version_id":"78486ff1-e996-4467-8952-3ebfbcd0bcfc"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Downbeat nystagmus associated with damage to the medial longitudinal fasciculus of the pons: A vestibular balance control mechanism via the lower brainstem paramedian tract neurons","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Downbeat nystagmus associated with damage to the medial longitudinal fasciculus of the pons: A vestibular balance control mechanism via the lower brainstem paramedian tract neurons"}]},"item_type_id":"5","owner":"1","path":["5480","335","1488","1354"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-07-19"},"publish_date":"2019-07-19","publish_status":"0","recid":"51726","relation_version_is_last":true,"title":["Downbeat nystagmus associated with damage to the medial longitudinal fasciculus of the pons: A vestibular balance control mechanism via the lower brainstem paramedian tract neurons"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T09:24:49.476675+00:00"}