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SNARE dynamics during melanosome maturation
http://hdl.handle.net/2241/00154056
http://hdl.handle.net/2241/0015405628f2949a-fb09-43a1-9e62-c0c6dd1355cc
名前 / ファイル | ライセンス | アクション |
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BST_46-4 (288.1 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2018-12-07 | |||||
タイトル | ||||||
タイトル | SNARE dynamics during melanosome maturation | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Ohbayashi, Norihiko
× Ohbayashi, Norihiko× Fukuda, Mitsunori |
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著者別名 |
大林, 典彦
× 大林, 典彦 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Historically, studies on the maturation and intracellular transport of melanosomes in melanocytes have greatly contributed to elucidating the general mechanisms of intracellular transport in many different types of mammalian cells. During melanosome maturation, melanosome cargoes including melanogenic enzymes (e.g. tyrosinase) are transported from endosomes to immature melanosomes by membrane trafficking, which must require a membrane fusion process likely regulated by SNAREs [soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptors]. In the present study, we review the literature concerning the expression and function of SNAREs (e.g. v-SNARE vesicle-associated membrane protein 7 and t-SNAREs syntaxin-3/13 and synaptosomal-associated protein-23) in melanocytes, especially in regard to the fusion process in which melanosome cargoes are finally delivered to immature melanosomes. We also describe the recent discovery of the SNARE recycling system on mature melanosomes in melanocytes. Such SNARE dynamics, especially the SNARE recycling system, on melanosomes will be useful in understanding as yet unidentified SNARE dynamics on other organelles. | |||||
書誌情報 |
Biochemical Society transactions 巻 46, 号 4, p. 911-917, 発行日 2018-08 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0300-5127 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00564511 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 30026369 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1042/BST20180130 | |||||
権利 | ||||||
権利情報 | © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society | |||||
著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | Portland Press |