@article{oai:tsukuba.repo.nii.ac.jp:00046534,
 author = {上野, 友之 and 羽田, 康司 and Ueno, Tomoyuki and Hada, Yasushi and Shimizu, Yukiyo and Yamada, Thoru},
 issue = {6},
 journal = {International journal of neuroscience},
 month = {Jun},
 note = {Purpose: The somatosensory event-related potential N140 is thought to be related to selective attention. This study aimed to compare the somatosensory event-related potential N140 in healthy subjects to that in patients with stroke to determine whether N140 and attentiveness are associated in patients with stroke with or without hemispatial agnosia.

Materials and Methods: Normal somatosensory event-related potential N140 values were determined using data from ten healthy subjects. Fifteen patients with stroke were divided into two groups based on the presence of hemispatial neglect. Somatosensory event-related potential N140 components were compared between the two groups.

Results: Stimulation of the affected limb in the hemispatial agnosia group resulted in significantly longer N140 latency at the contralateral vs. the ipsilateral electrode. This was the inverse of the relationship observed in normal subjects, with stimulation of the intact side in patients with hemispatial agnosia, and with stimulation of both the intact and affected sides in patients without agnosia. In the hemispatial agnosia group, the peak latency of N140 following stimulation of the affected side was significantly longer than it was following stimulation of the intact side and when compared to that in patients without agnosia. In addition, abnormal N140 peak latencies were observed at the Cz and ipsilateral electrodes in patients with hemispatial agnosia following stimulation of the intact side.

Conclusions: These findings suggest that somatosensory event-related potential N140 is independently generated in each hemisphere and may reflect cognitive attention.},
 pages = {487--494},
 title = {Relationship between somatosensory event-related potential N140 aberrations and hemispatial agnosia in patients with stroke: a preliminary study},
 volume = {128},
 year = {2018}
}