{"created":"2021-03-01T07:26:23.501575+00:00","id":46472,"links":{},"metadata":{"_buckets":{"deposit":"76257c5c-6d22-4159-af80-39fa58bb6e50"},"_deposit":{"id":"46472","owners":[],"pid":{"revision_id":0,"type":"depid","value":"46472"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00046472","sets":["160:2174","3:62:5596:6620"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageStart":"222","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"Neural Regeneration Research"}]}]},"item_5_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鶴田, 文憲"}],"nameIdentifiers":[{},{},{}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Microglia are the resident immune cells of the central nervous system (CNS). In the normal state, microglia have a ramified shape and continuously survey the conditions of the brain. In response to various stimuli, some microglia change to an amoeboid shape. This type of microglia is motile and produces several secretory proteins, including inflammatory cytokines and neurotrophic factors, which regulate brain homeostasis. Microglial morphology also changes a great deal in concert with environmental factors during brain development, and related to microglial migration and proliferation, which contribute to the establishment of precise synaptic connectivity and neural circuits. In this review, we focus on the fundamental concepts of microglial fate during brain development, and discuss whether the molecular mechanisms that control microglial morphology are linked to microglial functions.\n","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Medknow"}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"29557363","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.4103/1673-5374.226386","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-Shar-eAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under identical terms."}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1673-5374","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tsuruta, Fuminori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okajima, Tomomi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-05-22"}],"displaytype":"detail","filename":"NRR_13-2.pdf","filesize":[{"value":"225.9 kB"}],"format":"application/pdf","licensetype":"license_10","mimetype":"application/pdf","url":{"label":"NRR_13-2","url":"https://tsukuba.repo.nii.ac.jp/record/46472/files/NRR_13-2.pdf"},"version_id":"491c7c84-612c-4d9c-b652-d786b6609384"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Microglial dynamics during brain development","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Microglial dynamics during brain development"}]},"item_type_id":"5","owner":"1","path":["2174","6620"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-22"},"publish_date":"2018-05-22","publish_status":"0","recid":"46472","relation_version_is_last":true,"title":["Microglial dynamics during brain development"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T09:18:23.898287+00:00"}