{"created":"2021-03-01T07:19:21.928926+00:00","id":40031,"links":{},"metadata":{"_buckets":{"deposit":"2fea8cef-01da-46ea-9def-97240ecccddf"},"_deposit":{"id":"40031","owners":[],"pid":{"revision_id":0,"type":"depid","value":"40031"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00040031","sets":["2780:961","3:62:5592:418"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"590","bibliographicPageStart":"581","bibliographicVolumeNumber":"130","bibliographic_titles":[{"bibliographic_title":"Journal of neuro-oncology"}]}]},"item_5_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本 , 哲哉"}],"nameIdentifiers":[{}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We aimed to reappraise whether post-stereotactic radiosurgery (SRS) results for brain metastases differ between patients with and without neurological symptoms. This was an institutional review board-approved, retrospective cohort study using our prospectively accumulated database including 2825 consecutive BM patients undergoing gamma knife SRS alone during the 15-year period since July 1998. The 2825 patients were divided into two groups; neurologically asymptomatic [group A, 1374 patients (48.6 %)] and neurologically symptomatic [group B, 1451 (51.4 %)]. Because there was considerable bias in pre-SRS clinical factors between groups A and B, a case-matched study was conducted. Ultimately, 1644 patients (822 in each group) were selected. The standard Kaplan–Meier method was used to determine post-SRS survival. Competing risk analysis was applied to estimate cumulative incidences of neurological death, neurological deterioration, local recurrence, re-SRS for new lesions and SRS-induced complications. Post-SRS median survival times (MSTs) did not differ between the two groups; 7.8 months in group A versus 7.4 months in group B patients (HR 1.064, 95 % CI 0.963–1.177, p = 0.22). However, cumulative incidences of neurological death (HR 1.637, 95 % CI 1.174–2.281, p = 0.0036) and neurological deterioration (HR 1.425, 95 % CI 1.073–1.894, p = 0.014) were significantly lower in the group A than in the group B patients. Neurologically asymptomatic patients undergoing SRS for BM had better results than symptomatic patients in terms of both maintenance of good neurological state and prolonged neurological survival. Thus, we conclude that screening computed tomography/magnetic resonance imaging is highly beneficial for managing cancer patients.","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Science+Business Media "}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"27591775","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s11060-016-2264-0","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2016. This article is published with open access at Springerlink.com"},{"subitem_rights":"This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons. org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made."}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0167-594X","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10633712 ","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Koiso, Takao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Masaaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawabe, Takuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Shinya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Yasunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Higuchi, Yoshinori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Tetsuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumura, Akira"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kasuya, Hidetoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Barfod, Bierta E."}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-16"}],"displaytype":"detail","filename":"JNO_130-3.pdf","filesize":[{"value":"638.9 kB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"JNO_130-3","url":"https://tsukuba.repo.nii.ac.jp/record/40031/files/JNO_130-3.pdf"},"version_id":"79cb56c1-9193-406a-a613-bdc8562f5ee3"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A case-matched study of stereotactic radiosurgery for patients with brain metastases: comparing treatment results for those with versus without neurological symptoms","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A case-matched study of stereotactic radiosurgery for patients with brain metastases: comparing treatment results for those with versus without neurological symptoms"}]},"item_type_id":"5","owner":"1","path":["961","418"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-01-16"},"publish_date":"2017-01-16","publish_status":"0","recid":"40031","relation_version_is_last":true,"title":["A case-matched study of stereotactic radiosurgery for patients with brain metastases: comparing treatment results for those with versus without neurological symptoms"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T09:10:22.414548+00:00"}