@article{oai:tsukuba.repo.nii.ac.jp:00037398,
 author = {渋谷, 彰 and 渋谷, 和子 and Anh Van Vo and Takenaka, Eri and Shibuya, Akira and Shibuya, Kazuko},
 journal = {Molecular immunology},
 month = {Jan},
 note = {DNAM-1 is an activating receptor expressed on NK cells and T cells and plays an important role in cytotoxicity of these cells against target cells. Although the role of DNAM-1 in the function of T cells and NK cells has been well studied, the expression and function of DNAM-1 on myeloid cells have been incompletely understood. In this study, we investigated expression of DNAM-1 on monocyte subsets in mouse peripheral blood and found that only inflammatory monocytes (iMos), but not patrolling monocytes (pMos), expressed high levels of DNAM-1. In addition, we found that DNAM-1 was highly expressed on iMos, rather than pMos, also in human. Furthermore, we found that DNAM-1 on inflammatory monocytes was involved in cell adhesion to CD155-expressing cells. Therefore, we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule on blood inflammatory monocytes.},
 pages = {70--76},
 title = {Expression of DNAM-1 (CD226) on inflammatory monocytes},
 volume = {69},
 year = {2016}
}