@article{oai:tsukuba.repo.nii.ac.jp:00032712, author = {田中, 誠 and Ishitsuka, S. and Kusuyama, N. and Tanaka, M.}, issue = {6}, journal = {Neurophysiology}, month = {Dec}, note = {The recently introduced “squatting test” (ST) utilizes a simple postural change to perturb the blood pressure and to assess baroreflex sensitivity (BRS). In our study, we estimated the reproducibility of and the optimal testing interval between the STs in healthy volunteers. Thirty-four subjects free of cardiovascular disorders and taking no medication were instructed to perform the repeated ST at 30-sec, 1-min, and 3-min intervals in duplicate in a random sequence, while the systolic blood pressure (SBP) and pulse intervals were measured. Baroreflex sensitivity was estimated by plotting reflex increases and decreases in the SBP and succeeding pulse intervals during stand-to-squat and squat-tostand maneuvers, respectively. Correlations between duplicate BRS data at each testing interval were analyzed by the Pearson’s correlation coefficient, while agreements were assessed by Bland-Altman plots. Two measurements of BRS during stand-to-squat and squat-to-stand maneuvers demonstrated significant correlations at both 1-min and 3-min intervals, while at 30-sec intervals correlation was poor. Correlation coefficients became considerably greater in each maneuver as the measurement interval was increased from 30 sec to 3 min. Our results suggest that the testing interval in the ST should be at least 1 min long, but ideally it should be longer than or equal to 3 min, to assess the baroreflex adequately.}, pages = {494--500}, title = {Optimal Testing Intervals in the Squatting Test to Determine Baroreflex Sensitivity}, volume = {46}, year = {2014} }