{"created":"2021-03-01T07:08:01.958342+00:00","id":29535,"links":{},"metadata":{"_buckets":{"deposit":"dbdf3766-210f-4420-98f4-762f07428cca"},"_deposit":{"id":"29535","owners":[],"pid":{"revision_id":0,"type":"depid","value":"29535"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00029535","sets":["2780:2607","2780:2608","2780:2609","2780:2612","3:62:5601:2568"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"116","bibliographicPageStart":"112","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"Seizure"}]}]},"item_5_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安部, 加奈子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"濱田, 洋実"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"小畠, 真奈"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"吉川, 裕之"}],"nameIdentifiers":[{}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose\n\nTo investigate whether planning of pregnancy in women with epilepsy affects seizure control during pregnancy and to compare the maternal and neonatal outcomes in planned and unplanned pregnancies.\nMethods\n\nThis was a retrospective cohort study of 153 pregnant women with epilepsy who were treated at the University of Tsukuba Hospital and Hokkaido University Hospital between 2003 and 2011. Twenty-one pregnancies were excluded due to insufficient data. Data of patients followed by neurologists during their planned pregnancies (planned-pregnancy group, n = 51) were compared to those of patients referred to neurologists after conception for managing epilepsy during pregnancy (unplanned-pregnancy group, n = 81). The treatment profile for epilepsy, seizure control, and maternal and neonatal outcomes in both groups were compared using Chi-square test or Fisher's exact test and Mann–Whitney U test.\nResults\n\nCompared to the unplanned-pregnancy group, the planned-pregnancy group showed a significantly greater proportion of patients receiving monotherapy with antiepileptic drugs (80% vs. 61%: planned vs. unplanned, P = 0.049) and those not requiring valproic acid (77% vs. 56%, P = 0.031). Furthermore, the frequency of epileptic seizures (16% vs. 35%, P = 0.018) and changes in antiepileptic drugs (24% vs. 41%, P = 0.042) were significantly lower in the planned-pregnancy group than in the unplanned-pregnancy group. No significant intergroup differences were noted in the obstetric complications and neonatal outcomes, including congenital malformations.\nConclusion\n\nFor women with epilepsy, planning of pregnancy is associated with good seizure control during pregnancy and less fetal exposure to antiepileptic drugs.","subitem_description_type":"Abstract"}]},"item_5_identifier_34":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2241/121187"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Ltd."}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"24183922","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.seizure.2013.10.003","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 British Epilepsy Association"},{"subitem_rights":"NOTICE: this is the author’s version of a work that was accepted for publication in　Seizure. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Seizure, 23, 2, 2014.http://dx.doi.org/10.1/j.seizure.2013.10.003."}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1059-1311","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA1091615X","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Abe, Kanako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hamada, Hiromi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamada, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Obata-Yasuoka, Mana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Minakami, Hisanori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshikawa, Hiroyuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2014-05-09"}],"displaytype":"detail","filename":"Seizure_23-2.pdf","filesize":[{"value":"258.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Seizure_23-2.pdf","url":"https://tsukuba.repo.nii.ac.jp/record/29535/files/Seizure_23-2.pdf"},"version_id":"230abadf-1b95-4d61-bb4b-97b91d7f31c0"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Impact of planning of pregnancy in women with epilepsy on seizure control during pregnancy and on maternal and neonatal outcomes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Impact of planning of pregnancy in women with epilepsy on seizure control during pregnancy and on maternal and neonatal outcomes"}]},"item_type_id":"5","owner":"1","path":["2608","2609","2612","2607","2568"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-04-03"},"publish_date":"2014-04-03","publish_status":"0","recid":"29535","relation_version_is_last":true,"title":["Impact of planning of pregnancy in women with epilepsy on seizure control during pregnancy and on maternal and neonatal outcomes"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T08:58:03.584535+00:00"}