{"created":"2021-03-01T07:07:46.416981+00:00","id":29296,"links":{},"metadata":{"_buckets":{"deposit":"5a04f8bf-a8d4-48c6-b2ce-b1a925457069"},"_deposit":{"id":"29296","owners":[],"pid":{"revision_id":0,"type":"depid","value":"29296"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00029296","sets":["2780:984","3:62:5595:431","7131:543"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-2","bibliographicPageEnd":"27","bibliographicPageStart":"23","bibliographicVolumeNumber":"56","bibliographic_titles":[{"bibliographic_title":"Molecular immunology"}]}]},"item_5_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"本多, 伸一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渋谷, 彰"}],"nameIdentifiers":[{},{},{}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fcα/μR (CD351) is an Fc receptor for both IgA and IgM and forms an atypical dimer that is resistant to reduction by 2-mercaptoethanol or boiling. We previously demonstrated that the cytoplasmic portion of Fcα/μR is required for dimer formation and for its efficient cell-surface expression. However, the biochemical nature of these phenomena has not been determined. By using a BW5147 mouse cell line expressing deletion mutants of the cytoplasmic region of Fcα/μR, we found that the region spanning amino acids 504–523 was required for efficient cell-surface expression, whereas the region spanning amino acids 481–490 was required for dimmer formation. Immunoblotting analyses of transfectants simultaneously expressing Flag-tagged Fcα/μR and hemagglutinin-tagged Fcα/μR suggested that Fcα/μR does not form homodimers. Instead, our data suggest that Fcα/μR forms heterodimers with an as-yet-unknown molecule with a molecular weight of 60–70 kDa.","subitem_description_type":"Abstract"}]},"item_5_identifier_34":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2241/119620"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"23665380","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.molimm.2013.04.003","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 Elsevier Ltd.\nNOTICE: this is the author’s version of a work that was accepted for publication in Molecular immunology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Molecular immunology, 56(1-2),(2012) http://dx.doi.org/10.1016/j.molimm.2013.04.003."}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0161-5890","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00307483","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Takagaki, Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Satoh, Kazuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Honda, Shin-ichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shibuya, Akira"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-12-25"}],"displaytype":"detail","filename":"MI_56-1pdf.pdf","filesize":[{"value":"499.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"MI_56-1pdf.pdf","url":"https://tsukuba.repo.nii.ac.jp/record/29296/files/MI_56-1pdf.pdf"},"version_id":"db575e8a-ff3a-4ee5-b5c6-549999a1ed41"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Molecular characterization of the dimer formation of Fcα/μ receptor (CD351)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Molecular characterization of the dimer formation of Fcα/μ receptor (CD351)"}]},"item_type_id":"5","owner":"1","path":["543","984","431"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-09-02"},"publish_date":"2013-09-02","publish_status":"0","recid":"29296","relation_version_is_last":true,"title":["Molecular characterization of the dimer formation of Fcα/μ receptor (CD351)"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T08:57:40.242918+00:00"}