{"created":"2021-03-01T07:06:14.247279+00:00","id":27890,"links":{},"metadata":{"_buckets":{"deposit":"4da04784-c839-4caf-85f0-103da0fbe6b5"},"_deposit":{"id":"27890","owners":[],"pid":{"revision_id":0,"type":"depid","value":"27890"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:00027890","sets":["160:1470","2871:2873:296","29:297","3:62:5297:1814"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"19","bibliographicPageEnd":"5756","bibliographicPageStart":"5745","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"Bioorganic & medicinal chemistry"}]}]},"item_5_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"早川, 一郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"臼井, 健郎"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"木越, 英夫"}],"nameIdentifiers":[{},{},{}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Various analogues of glaziovianin A, an antitumor isoflavone, were synthesized, and their biological activities were evaluated. O7-modified glaziovianin A showed strong cytotoxicity against HeLa S3 cells. Compared to glaziovianin A, the O7-benzyl and O7-propargyl analogues were more cytotoxic against HeLa S3 cells and more potent M-phase inhibitors. Furthermore, O7-modified molecular probes of glaziovianin A were synthesized for biological studies.","subitem_description_type":"Abstract"}]},"item_5_identifier_34":{"attribute_name":"URI","attribute_value_mlt":[{"subitem_identifier_type":"HDL","subitem_identifier_uri":"http://hdl.handle.net/2241/117846"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"22921744","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.bmc.2012.08.005","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2012 Elsevier Ltd.\nNOTICE: this is the author’s version of a work that was accepted for publication in Bioorganic & medicinal chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, 20(19),2012  DOI:10.1016/j.bmc.2012.08.005"}]},"item_5_select_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0968-0896","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10938083","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayakawa, Ichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikedo, Akiyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chinen, Takumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Usui, Takeo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"木越, 英夫"},{"creatorName":"キゴシ, ヒデオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-12-25"}],"displaytype":"detail","filename":"BMC_20-19.pdf","filesize":[{"value":"593.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BMC_20-19.pdf","url":"https://tsukuba.repo.nii.ac.jp/record/27890/files/BMC_20-19.pdf"},"version_id":"56b332af-a39b-40dc-bf25-e97559c041b9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone"}]},"item_type_id":"5","owner":"1","path":["297","1470","296","1814"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-11-12"},"publish_date":"2012-11-12","publish_status":"0","recid":"27890","relation_version_is_last":true,"title":["Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone"],"weko_creator_id":"1","weko_shared_id":5},"updated":"2022-04-27T08:55:51.682207+00:00"}