{"created":"2021-11-08T04:40:45.578883+00:00","id":2001815,"links":{},"metadata":{"_buckets":{"deposit":"df104f89-8e2f-4f1d-b1b7-0838e8d5edbf"},"_deposit":{"created_by":52,"id":"2001815","owner":"52","owners":[52],"owners_ext":{"displayname":"kuro","username":"kuro"},"pid":{"revision_id":0,"type":"depid","value":"2001815"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:02001815","sets":["2780:1276","2780:1636349815647","2780:6392","2780:6989","3:62:5592:1636345958217"]},"author_link":["204326","204867","413","209391"],"control_number":"2001815","item_1644910766877":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"26","bibliographicPageStart":"22","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"Journal of Artificial Organs","bibliographic_titleLang":"en"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Roller pumping results in hemolysis and adverse effects on coagulation, but there are few reports on the influence of roller heads on platelets. Here, we evaluate the interaction between roller pumping and platelet function using a simulated extracorporeal circuit incorporating a vinyl chloride tube and roller head pump with 30 min recirculation. Platelet aggregation, platelet count, microparticle, P-selectin, Phosphatidylserine (PS) exposure and Ricinus Communis Agglutinin 1 (RCA-1) were measured before, 5, 10, 20, and 30 min after the recirculation using 100 ml of fresh human blood that had obtained from healthy volunteers (n = 9). Platelet aggregation and platelet count gradually decreased but microparticles significantly increased after the recirculation (P < 0.05). P-selectin, PS exposure and RCA-1 were measured using flow cytometry. There were no significant differences in the P-selectin and PS exposure expression during recirculation. RCA-1, a platelet apoptosis markers, significantly increased 30 min after recirculation (P < 0.05). We thus conclude that roller pumping induced platelet apoptosis and caused decreases in platelet count and aggregation after the recirculation.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_5_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"32620985","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s10047-020-01192-x","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Japanese Society for Artificial Organs 2020. This is a post-peer-review, pre-copyedit version of an article published in Journal of Artificial Organs. The final authenticated version is available online at https://doi.org/10.1007/s10047-020-01192-x.","subitem_rights_language":"en"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1434-7229","subitem_source_identifier_type":"PISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11283795","subitem_source_identifier_type":"NCID"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Furugaki, Tatsuya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shigeta, Osamu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kozuma, Yukinori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tsukada, Toru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakajima, Tomomi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"坂本, 裕昭","creatorNameLang":"ja"},{"creatorName":"サカモト, ヒロアキ","creatorNameLang":"ja-Kana"},{"creatorName":"SAKAMOTO, Hiroaki","creatorNameLang":"en"}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"マティス, ブライアン ジェームズ","creatorNameLang":"ja"},{"creatorName":"マティス, ブライアン ジェームズ","creatorNameLang":"ja-Kana"},{"creatorName":"MATHIS, Bryan James","creatorNameLang":"en"}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"平松, 祐司","creatorNameLang":"ja"},{"creatorName":"ヒラマツ, ユウジ","creatorNameLang":"ja-Kana"},{"creatorName":"HIRAMATSU, Yuji","creatorNameLang":"en"}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"鈴木, 保之","creatorNameLang":"ja"},{"creatorName":"スズキ, ヤスユキ","creatorNameLang":"ja-Kana"},{"creatorName":"SUZUKI, Yasuyuki","creatorNameLang":"en"}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-04"}],"displaytype":"detail","filename":"JAO-24_1_22.pdf","filesize":[{"value":"380 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tsukuba.repo.nii.ac.jp/record/2001815/files/JAO-24_1_22.pdf"},"version_id":"66ccf5ac-4518-485f-b94a-77af97af51de"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation","subitem_title_language":"en"}]},"item_type_id":"5","owner":"52","path":["1636345958217","6989","1636349815647","1276","6392"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-11-08"},"publish_date":"2021-11-08","publish_status":"0","recid":"2001815","relation_version_is_last":true,"title":["The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation"],"weko_creator_id":"52","weko_shared_id":-1},"updated":"2023-02-17T01:07:15.450514+00:00"}