{"created":"2021-11-08T04:40:45.578883+00:00","id":2001815,"links":{},"metadata":{"_buckets":{"deposit":"df104f89-8e2f-4f1d-b1b7-0838e8d5edbf"},"_deposit":{"created_by":221,"id":"2001815","owner":"52","owners":[221],"pid":{"revision_id":0,"type":"depid","value":"2001815"},"status":"published"},"_oai":{"id":"oai:tsukuba.repo.nii.ac.jp:02001815","sets":["3:62:1722555831928"]},"author_link":[],"item_1644910766877":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_1722561470159":{"attribute_name":"著者情報","attribute_value_mlt":[{"subitem_link_text":"医学医療系; 坂本, 裕昭; サカモト, ヒロアキ; SAKAMOTO, Hiroaki","subitem_link_url":"http://trios.tsukuba.ac.jp/researcher/0000003064"},{"subitem_link_text":"医学医療系; マティス, ブライアン ジェームズ; マティス, ブライアン　ジェームズ; MATHIS, Bryan　James","subitem_link_url":"http://trios.tsukuba.ac.jp/researcher/0000003913"},{"subitem_link_text":"筑波大学; 平松, 祐司; ヒラマツ, ユウジ; HIRAMATSU, Yuji","subitem_link_url":"http://trios.tsukuba.ac.jp/researcher/0000001916"},{"subitem_link_text":"医学医療系; 鈴木, 保之; スズキ, ヤスユキ; SUZUKI, Yasuyuki","subitem_link_url":"http://trios.tsukuba.ac.jp/researcher/0000004272"}]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"26","bibliographicPageStart":"22","bibliographicVolumeNumber":"24","bibliographic_titles":[{"bibliographic_title":"Journal of Artificial Organs","bibliographic_titleLang":"en"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Roller pumping results in hemolysis and adverse effects on coagulation, but there are few reports on the influence of roller heads on platelets. Here, we evaluate the interaction between roller pumping and platelet function using a simulated extracorporeal circuit incorporating a vinyl chloride tube and roller head pump with 30 min recirculation. Platelet aggregation, platelet count, microparticle, P-selectin, Phosphatidylserine (PS) exposure and Ricinus Communis Agglutinin 1 (RCA-1) were measured before, 5, 10, 20, and 30 min after the recirculation using 100 ml of fresh human blood that had obtained from healthy volunteers (n = 9). Platelet aggregation and platelet count gradually decreased but microparticles significantly increased after the recirculation (P < 0.05). P-selectin, PS exposure and RCA-1 were measured using flow cytometry. There were no significant differences in the P-selectin and PS exposure expression during recirculation. RCA-1, a platelet apoptosis markers, significantly increased 30 min after recirculation (P < 0.05). We thus conclude that roller pumping induced platelet apoptosis and caused decreases in platelet count and aggregation after the recirculation.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_5_publisher_27":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_5_relation_10":{"attribute_name":"PMID","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"32620985","subitem_relation_type_select":"PMID"}}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s10047-020-01192-x","subitem_relation_type_select":"DOI"}}]},"item_5_rights_12":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© The Japanese Society for Artificial Organs 2020. This is a post-peer-review, pre-copyedit version of an article published in Journal of Artificial Organs. The final authenticated version is available online at https://doi.org/10.1007/s10047-020-01192-x.","subitem_rights_language":"en"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1434-7229","subitem_source_identifier_type":"PISSN"}]},"item_5_source_id_9":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11283795","subitem_source_identifier_type":"NCID"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Furugaki, Tatsuya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shigeta, Osamu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kozuma, Yukinori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tsukada, Toru","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakajima, Tomomi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"SAKAMOTO, Hiroaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"MATHIS, Bryan James","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"HIRAMATSU, Yuji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"SUZUKI, Yasuyuki","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-04"}],"displaytype":"detail","filename":"JAO-24_1_22.pdf","filesize":[{"value":"380 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://tsukuba.repo.nii.ac.jp/record/2001815/files/JAO-24_1_22.pdf"},"version_id":"66ccf5ac-4518-485f-b94a-77af97af51de"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation","subitem_title_language":"en"}]},"item_type_id":"5","owner":"221","path":["1722555831928"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-11-08"},"publish_date":"2021-11-08","publish_status":"0","recid":"2001815","relation_version_is_last":true,"title":["The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation"],"weko_creator_id":"221","weko_shared_id":-1},"updated":"2024-12-29T15:24:53.462131+00:00"}