@article{oai:tsukuba.repo.nii.ac.jp:02001655,
 author = {Kitazawa, Shinsuke and 小林, 尚寛 and KOBAYASHI, Naohiro and Ueda, Sho and 榎本, 有希 and ENOMOTO, Yuki and 井上, 貴昭 and INOUE, Yoshiaki and 塩澤, 利博 and SHIOZAWA, Toshihiro and 関根, 郁夫 and SEKINE, Ikuo and Kawai, Hitomi and 野口, 雅之 and NOGUCHI, Masayuki and 佐藤, 幸夫 and SATO, Yukio},
 issue = {10},
 journal = {Thoracic Cancer},
 month = {Oct},
 note = {Endobronchial-invasive lung cancers are generally diagnosed at advanced stages and may require emergency treatment for airway obstruction. Stent implantation is a common intervention for such obstructed airways but certain subsets of patients cannot receive adequate treatment without respiratory support. Veno-venous extracorporeal membrane oxygenation (ECMO) is a salvage therapy for respiratory failure but its usefulness in managing patients with advanced lung cancer remains unclear given the poor prognosis. In recent years, molecular targeted agents for patients with driver mutations offer rapid responses and may be administered even while under critical care. In this report, we describe the case of 39-year-old female who presented to our emergency department with severe respiratory distress. A computed tomography scan revealed a large mediastinal tumor invading the tracheal carina causing severe stenosis of the left main bronchus and right main pulmonary artery. ECMO support was required as the respiratory condition remained unstable despite high pressure ventilation. Under ECMO support, the patient underwent bronchial stent implantation and was successfully weaned off ECMO. The tumor was histologically diagnosed as pulmonary adenocarcinoma with anaplastic lymphoma kinase gene rearrangement. Treatment with a tyrosine kinase inhibitor, alectinib, induced a marked tumor reduction within a short period. The patient recovered well and is now in remission one year later. This case indicates that intensive respiratory support with ECMO may become a bridge through the critical period for selected patients with respiratory failure secondary to advanced lung cancer.},
 pages = {3024--3028},
 title = {Successful use of extracorporeal membrane oxygenation for airway‐obstructing lung adenocarcinoma},
 volume = {11},
 year = {2020},
 yomi = {コバヤシ, ナオヒロ and エノモト, ユウキ and イノウエ, ヨシアキ and シオザワ, トシヒロ and セキネ, イクオ and ノグチ, マサユキ and サトウ, ユキオ}
}