@article{oai:tsukuba.repo.nii.ac.jp:02001548, author = {Hase, Yoshihiro and Satoh, Katsuya and Chiba, Atsuya and Hirano, Yoshimi and 冨田, 成夫 and TOMITA, Shigeo and Saito, Yuichi and Narumi, Kazumasa}, issue = {2}, journal = {Quantum Beam Science}, month = {May}, note = {Cluster ion beams have unique features in energy deposition, but their biological effects are yet to be examined. In this study, we employed bacterial spores as a model organism, established an irradiation method, and examined the lethal effect of 2 MeV C, 4 MeV C2, and 6 MeV C3 ion beams. The lethal effect per particle (per number of molecular ions) was not significantly different between cluster and monomer ion beams. The relative biological effectiveness and inactivation cross section as a function of linear energy transfer (LET) suggested that the single atoms of 2 MeV C deposited enough energy to kill the spores, and, therefore, there was no significant difference between the cluster and monomer ion beams in the cell killing effect under this experimental condition. We also considered the behavior of the atoms of cluster ions in the spores after the dissociation of cluster ions into monomer ions by losing bonding electrons through inelastic collisions with atoms on the surface. To the best of our knowledge, this is the first report to provide a basis for examining the biological effect of cluster ions.}, title = {Experimental Study on the Biological Effect of Cluster Ion Beams in Bacillus subtilis Spores}, volume = {3}, year = {2019}, yomi = {トミタ, シゲオ} }