@article{oai:tsukuba.repo.nii.ac.jp:02001264, author = {Nagasaki, Kazuya and Gomi, Harumi and Ishioka, Haruhiko and Taguchi, Shijima and 髙屋敷, 典生 and TAKAYASHIKI, Norio and 小林, 裕幸 and KOBAYASHI, Hiroyuki}, journal = {IDCases}, month = {Apr}, note = {We report the case of a 71-year-old Japanese man with a history of chronic kidney disease and sarcoidosis receiving chronic corticosteroids who presented with disseminated Nocardia brasiliensis infection. He initially showed improvement with empiric antimicrobial therapy including trimethoprim-sulfamethoxazole. However, he deteriorated after modifying the empiric regimen due to complicated hyperkalemia and ultimately died. In general, elderly patients have decreased renal function. Standard therapy for nocardiosis with trimethoprim-sulfamethoxazole may not be used for a prolonged period of time. This case emphasizes the challenges and importance of prudent selection of empiric antimicrobial therapy for disseminated nocardiosis in elderly patients with underlying kidney disease.}, title = {Challenges in treatment of disseminated nocardiosis in an elderly patient with renal failure on corticosteroids: a case report}, volume = {20}, year = {2020}, yomi = {タカヤシキ, ノリオ and コバヤシ, ヒロユキ} }