@article{oai:tsukuba.repo.nii.ac.jp:00015360, author = {那須, 克宏 and 南, 学 and Nasu, Katsuhiro and Kuroki, Yoshifumi and Fujii, Hirofumi and Minami, Manabu}, issue = {4}, journal = {Magnetic resonance materials in physics, biology and medicine}, month = {Oct}, note = {application/pdf, Purpose: Hepatic pseudo-anisotropy is an artifact observed in hepatic diffusion-weighted imaging under respiratory triggering (RT-DWI). To determine the clinical significance of this phenomenon, hepatic RT-DW images were reviewed. Methods: One hundred and five MR examinations, including RT-DWI, were assessed. The patient group included 62 non-cirrhotic and 43 cirrhotic individuals. All images were evaluated by mutual agreement of two radiologists from the viewpoints of incidence of pseudo-anisotropy and correlation between pseudo-anisotropy and the quality of trace images. The ADC of normal hepatic parenchyma of non-cirrhotic livers were measured in both areas with and without pseudo-anisotropy. Results: Pseudo-anisotropy was observed in 60% of non-cirrhotic (37/62) and 30% of cirrhotic (13/43) images. The difference between the two groups was statistically significant (P < 0.001). The quality of trace images showed a tendency to worsen as pseudo-anisotropy became significant. However, the quality of trace images was generally satisfactory, with only two patients whose trace images were difficult to interpret due to pseudo-anisotropy. The areas with pseudo-anisotropy showed higher ADC than those without pseudo-anisotropy (P < 0.001). Conclusion: Pseudo-anisotropy is a type of artifact that originates from respiratory movement. Even though respiratory triggering is employed, ADC measurement of the liver is inaccurate because of pseudo-anisotropy, especially in non-cirrhotic patients.}, pages = {205--211}, title = {Hepatic pseudo-anisotropy: a specific artifact in hepatic diffusion-weighted images obtained with respiratory triggering}, volume = {20}, year = {2007} }