2024-03-28T14:20:23Z
https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:00055856
2022-04-27T09:30:42Z
2780:1283
2780:1781
2780:1975
3:62:5595:7291
Three cases of hepatocellular carcinoma treated 4times with proton beams
奥村, 敏之
オクムラ, トシユキ
OKUMURA, Toshiyuki
水本, 斉志
ミズモト, マサシ
MIZUMOTO, Masashi
櫻井, 英幸
サクライ, ヒデユキ
SAKURAI, Hideyuki
Murakami, Motohiro
Fukumitsu, Nobuyoshi
Numajiri, Haruko
Murofushi, Keiko
Ohnishi, Kayoko
Ishikawa, Hitoshi
Tsuboi, Koji
HCC may recur following surgery or radiofrequency ablation. Proton beam therapy (PBT) is a type of radiotherapy that achieves excellent local control of HCC without severe toxicity. The present study reported the long‑term outcome of 3 HCC patients who each received 4 repeat courses of PBT. All patients had a hepatitis B or C viral infection. A total of 14 lesions were treated using a curative PBT protocol and irradiated liver volumes in each treatment were 7‑50% of the total liver volume. Liver function in all cases was considerably preserved until the last follow‑up and patient survival was 51‑107 months from the first PBT with no local recurrence observed in the 14 lesions. The presented cases indicated that repeated PBT is an effective treatment option for recurrent HCC due to reduced liver damage and superior local treatment compared with other treatment options such as transarterial chemoembolization.
journal article
Spandidos Publications
2019-01
application/pdf
Molecular and clinical oncology
1
12
31
35
2049-9450
AA12610944
https://tsukuba.repo.nii.ac.jp/record/55856/files/MCO_12-1-31.pdf
eng
31814974
10.3892/mco.2019.1950
© Murakami et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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