2024-03-29T11:56:36Z
https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:00054080
2022-04-27T09:28:14Z
2780:340
3:62:5298:7831
Green tea consumption and risk of hematologic neoplasms: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)
山岸, 良匡
ヤマギシ, カズマサ
YAMAGISHI, Kazumasa
Takada, Midori
Iso, Hiroyasu
Tamakoshi, Akiko
Purpose
Experimental studies suggested that green tea may have an anticancer effect on hematologic neoplasms. However, few prospective studies have been conducted.
Methods
A total of 65,042 individuals aged 40–79 years participated in this study and completed a self-administered questionnaire about their lifestyle and medical history at baseline (1988–1990). Of these, 52,462 individuals living in 24 communities with information on incident hematologic neoplasms available in the cancer registry, who did not have a history of cancer and provided valid information on frequency of green tea consumption, were followed through 2009. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the incidence of hematologic neoplasms according to green tea consumption were analyzed.
Results
The incidence of hematologic neoplasms during a median follow-up of 13.3 years was 323. Compared with the never-drinkers of green tea, the multivariate HRs and 95% CIs for total hematologic neoplasms in green tea drinkers of ≤ 2 cups/day, 3–4 cups/day, and ≥ 5 cups/day were 0.65 (0.42–1.00), 0.73 (0.47–1.13), and 0.63 (0.42–0.96), respectively. The association was more prominent for acute myeloid leukemias and follicular lymphomas.
Conclusions
The present cohort study suggests a protective effect of green tea against hematologic neoplasms, especially acute myeloid leukemias.
journal article
Springer
2019-11
application/pdf
Cancer causes & control
11
30
1223
1230
0957-5243
AA10825145
https://tsukuba.repo.nii.ac.jp/record/54080/files/CCC_30-11.pdf
eng
31452000
10.1007/s10552-019-01220-z
© Springer Nature Switzerland AG 2019
This is a post-peer-review, pre-copyedit version of an article published in Cancer Causes & Control. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10552-019-01220-z