2024-03-29T01:32:28Z
https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:00052417
2022-04-27T09:25:55Z
160:6459
3:62:5297:4936
Ergothioneine production with Aspergillus oryzae
大津, 厳生
オオツ, イワオ
OHTSU, Iwao
Takusagawa, Shun
Satoh, Yasuharu
Dairi, Tohru
To establish a reliable and practical ergothioneine (ERG) supply, we employed fermentative ERG production using Aspergillus oryzae, a fungus used for food production. We heterologously overexpressed the egt-1 and -2 genes of Neurospora crassa in A. oryzae and succeeded in producing ERG (231.0 mg/kg of media, which was 20 times higher than the wild type).
Abbreviations: ERG: ergothioneine; HER: hercynine; Cys-HER: hercynylcysteine-sulfoxide; SAM: S-adenosylmethionine; SAH: S-adenosylhomocysteine; l-His: l-histidine; l-Cys: l-cysteine; LC-ESI-MS: liquid chromatography-electrospray ionization-mass spectrometry
journal article
TAYLOR & FRANCIS
2018-10
application/pdf
Bioscience, biotechnology, and biochemistry
1
83
181
184
0916-8451
AA10824164
https://tsukuba.repo.nii.ac.jp/record/52417/files/BBB_83-1-181.pdf
eng
30286703
10.1080/09168451.2018.1527210
This is an Accepted Manuscript of an article published by Taylor & Francis in Bioscience, Biotechnology, and Biochemistry on Volume 83, Issue 1, 2019 available online: http://www.tandfonline.com/10.1080/09168451.2018.1527210