2024-03-29T14:25:42Z
https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:00049499
2022-04-27T09:22:04Z
2780:1495
2780:1501
2780:2204
3:62:5592:2560
Proton Beam Therapy for Ameloblastic Carcinoma of the Maxilla: Report of a Rare Case
山縣, 憲司
ヤマガタ, ケンジ
YAMAGATA, Kenji
石川, 仁
イシカワ, ヒトシ
ISHIKAWA, Hitoshi
武川, 寛樹
ブカワ, ヒロキ
BUKAWA, Hiroki
Saito, Takashi
Ameloblastic carcinoma (AC) is a rare malignant odontogenic tumor that combines the histologic features of ameloblastoma with those of cytologic atypia. The standard treatment for this lesion is wide local excision. Proton beam therapy (PBT) can deliver high irradiation doses to the target and avoid irradiation to surrounding normal tissues, but no reports of PBT for AC have been published thus far. This report describes the case of a 70-year-old woman with a pathologic diagnosis of maxillary AC who refused surgical resection and received hypofractionated PBT at a total dose of 69 Gy in 23 fractions. She has been alive for more than 5 years after PBT without any evidence of recurrence and side effects. This is the first reported case of successful treatment after curative radiation therapy for maxillary AC.
journal article
Elsevier
American Association of Oral and Maxillofacial Surgeons
2019-01
application/pdf
Journal of oral and maxillofacial surgery
1
77
227.e1
227.e5
02782391
AA10628202
https://tsukuba.repo.nii.ac.jp/record/49499/files/JOMS_77-1.pdf
eng
30240599
10.1016/j.joms.2018.08.014
© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/