2024-03-28T18:54:45Z
https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:00033426
2022-04-27T09:01:49Z
2778:3031
2778:332
2871:2876:907
3:62:5296:3030
Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women
赤澤, 暢彦
鰺坂, 隆一
前田, 清司
Akazawa, Nobuhiko
Choi, Youngju
Miyaki, Asako
Tanabe, Yoko
Sugawara, Jun
Ajisaka, Ryuichi
Maeda, Seiji
Background
Reduction in arterial compliance with aging increases the risk of cardiovascular disease. Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of turmeric, is an anti-inflammatory agent. Therefore, it is plausible to hypothesize that curcumin improves arterial compliance. We investigated the effects of curcumin ingestion alone and in combination with aerobic exercise training on arterial compliance in postmenopausal women.
Methods
A total of 51 postmenopausal women were assigned to 4 groups: placebo, curcumin, exercise and placebo (Ex + placebo), and exercise and curcumin (Ex + curcumin). Curcumin or placebo was ingested orally for 8 weeks. The exercise groups underwent moderate aerobic exercise training for 8 weeks.
Results
Carotid arterial compliance increased significantly in the curcumin, Ex + placebo, and Ex + curcumin groups, whereas no such changes were observed in the placebo control group. The magnitude of increases in carotid arterial compliance was the greatest in the Ex + curcumin group.
Conclusion
We concluded that curcumin ingestion improves carotid arterial compliance and that the combination of curcumin and aerobic exercise training was more efficacious in increasing central arterial compliance than either of these treatments alone in postmenopausal women.
journal article
Elsevier B.V.
2013-03
application/pdf
Artery research
1
7
67
72
1872-9312
AA12384517
https://tsukuba.repo.nii.ac.jp/record/33426/files/AR_7-1.pdf
eng
10.1016/j.artres.2012.09.003
© 2012 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V.
NOTICE: this is the author’s version of a work that was accepted for publication in Artery research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Artery research, 7, 1, 2013, DOI:10.1016/j.artres.2012.09.003