2024-03-29T04:52:28Z
https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:02001250
2022-04-27T10:53:03Z
2780:6672
3:62:5297:7895
Effectiveness of enhanced cognitive behavior therapy for bulimia nervosa in Japan: a randomized controlled trial protocol
Ohara, Chisato
Sekiguchi, Atsushi
Takakura, Shu
Endo, Yuka
Tamura, Naho
Kikuchi, Hiroe
丸尾, 和司
マルオ, カズシ
MARUO, Kazushi
Sugawara, Norio
Hatano, Kenji
Kawanishi, Hitomi
Funaba, Misako
Sugawara, Ayako
Nohara, Nobuhiro
Kawai, Keisuke
Fukudo, Shin
Sudo, Nobuyuki
Cooper, Zafra
Yoshiuchi, Kazuhiro
Ando, Tetsuya
open access
© The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Background
The effectiveness of psychotherapeutic interventions for eating disorders (EDs) is widely studied in Europe, North America, and Australia/New Zealand. However, few controlled studies and no randomized controlled trials (RCTs) have been conducted in Japan despite the relatively high prevalence of EDs in the Japanese population. The aim of this study is to evaluate the effect of enhanced cognitive behavior therapy (CBT-E), an evidence-supported ED-focused form of cognitive behavior therapy (CBT), for the treatment of bulimia nervosa (BN) in Japan.
Methods/design
This multicenter RCT will compare CBT-E with treatment as usual (TAU), which is widely used in Japan. A group of 140 adult outpatients with a Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) diagnosis of BN, ≥18 years of age, a body mass index (BMI) > 17.5 and < 40 kg/m2 will be randomly assigned to CBT-E or TAU. Participants will be stratified by intervention site and BN severity. CBT-E participants will receive 20 sessions of focused form CBT-E for 20 weeks. Those in the TAU group will receive routine treatment provided by specialists. Assessment will be performed in a blinded manner prior to the start of treatment, after 6 weeks of treatment, at the end of treatment (20 weeks), and at follow-up at 40 and 80 weeks after the start of treatment. The primary outcome is the remission of BN, defined by the absence, in the previous 4 weeks, of symptoms required to meet the DSM-5 criteria for a diagnosis of BN. Secondary outcomes include the levels of ED psychopathology and impairment due to the ED, anxiety, depression, family function, and satisfaction with treatment.
Discussion
This will be the first RCT conducted in Japan to compare CBT-E and TAU for the treatment of BN. If CBT-E is found to be more effective than TAU, then the evidence would support its wider use for patients with BN in Japan. Because it is possible to train therapists who do not possess extensive specialist experience, wider use is also likely to be practically feasible. In addition, demonstrating the effectiveness of CBT-E in Japan would demonstrate that it could be successfully extended to additional world cultures and regions.
BMC
2020-02
eng
journal article
http://hdl.handle.net/2241/0002001250
https://tsukuba.repo.nii.ac.jp/records/2001250
32123540
https://doi.org/10.1186/s13030-020-0174-z
1751-0759
BioPsychoSocial Medicine
14
1
2
https://tsukuba.repo.nii.ac.jp/record/2001250/files/BPSM_14-1.pdf
application/pdf
693 KB
2021-09-13