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https://tsukuba.repo.nii.ac.jp/oai
oai:tsukuba.repo.nii.ac.jp:00025045
2022-04-27T08:52:40Z
117:810
2871:2873:808
3:62:5297:569
Spatio-temporal detachment of single cells using microarrayed transparent electrodes
福田, 淳二
鈴木, 博章
Fukuda, Junji
Kameoka, Yoshiaki
Suzuki, Hiroaki
© 2011 Elsevier Ltd.
NOTICE: this is the author's version of a work that was accepted for publication in Biomaterials. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Biomaterials, Vol.32 Issue 28, Pages:6663-6669. doi:10.1016/j.biomaterials.2011.05.068
This paper describes a dynamic cell manipulation approach by which cells can be selectively detached from transparent indium tin oxide (ITO) electrodes via electrochemical desorption of a self-assembled monolayer (SAM) of alkanethiol. Changes in the surface properties of ITO following modification and electrical desorption of the SAM were characterized. By using these reactions on ITO, cells were readily attached and then detached from ITO electrodes in a very rapid manner, with greater than 90% of the cells being detached within 5 min. Furthermore, we fabricated micropatterns of ITO electrodes using photolithography. Cells on the micropatterned ITO electrodes could be detached with single-cell resolution. This approach could potentially lead to on-demand harvesting or elimination of one population from others under microscopy, for a wide range of purposes.
Elsevier Science Ltd.
2011-10
eng
journal article
http://hdl.handle.net/2241/113887
https://tsukuba.repo.nii.ac.jp/records/25045
10.1016/j.biomaterials.2011.05.068
0142-9612
AA00110092
Biomaterials
32
28
6663
6669
https://tsukuba.repo.nii.ac.jp/record/25045/files/BM_32-28.pdf
application/pdf
1.2 MB
2013-12-25