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What Happens in the Staphylococcal Nucleoid under Oxidative Stress?
http://hdl.handle.net/2241/00161226
http://hdl.handle.net/2241/0016122653df5dda-ad40-48ec-b362-388a2db869f0
名前 / ファイル | ライセンス | アクション |
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microorganisms_7-12 (2.7 MB)
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Item type | Journal Article(1) | |||||||||||
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公開日 | 2020-09-08 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | What Happens in the Staphylococcal Nucleoid under Oxidative Stress? | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
資源タイプ | ||||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
タイプ | journal article | |||||||||||
著者 |
森川, 一也
× 森川, 一也× 大庭, 良介× 宮腰, 昌利
WEKO
204908
× Ushijima, Yuri× Takeyasu, Kunio |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | The evolutionary success of Staphylococcus aureus as an opportunistic human pathogen is largely attributed to its prominent abilities to cope with a variety of stresses and host bactericidal factors. Reactive oxygen species are important weapons in the host arsenal that inactivate phagocytosed pathogens, but S. aureus can survive in phagosomes and escape from phagocytic cells to establish infections. Molecular genetic analyses combined with atomic force microscopy have revealed that the MrgA protein (part of the Dps family of proteins) is induced specifically in response to oxidative stress and converts the nucleoid from the fibrous to the clogged state. This review collates a series of evidences on the staphylococcal nucleoid dynamics under oxidative stress, which is functionally and physically distinct from compacted Escherichia coli nucleoid under stationary phase. In addition, potential new roles of nucleoid clogging in the staphylococcal life cycle will be proposed. | |||||||||||
書誌情報 |
en : Microorganisms 巻 7, 号 12, p. 631, 発行日 2019-11 |
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ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 2076-2607 | |||||||||||
PubMed番号 | ||||||||||||
識別子タイプ | PMID | |||||||||||
関連識別子 | 31795457 | |||||||||||
DOI | ||||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | 10.3390/microorganisms7120631 | |||||||||||
権利 | ||||||||||||
権利情報 | © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | |||||||||||
著者版フラグ | ||||||||||||
値 | publisher | |||||||||||
出版者 | ||||||||||||
出版者 | MDPI |