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NommPred: Prediction of Mitochondrial and Mitochondrion-Related Organelle Proteins of Nonmodel Organisms
http://hdl.handle.net/2241/00155452
http://hdl.handle.net/2241/001554528f1e0e4e-84f2-4e2c-8e10-38d6f8b786cc
名前 / ファイル | ライセンス | アクション |
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EB_14-1 (767.5 kB)
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Item type | Journal Article(1) | |||||||||||||||||
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公開日 | 2019-05-16 | |||||||||||||||||
タイトル | ||||||||||||||||||
タイトル | NommPred: Prediction of Mitochondrial and Mitochondrion-Related Organelle Proteins of Nonmodel Organisms | |||||||||||||||||
言語 | ||||||||||||||||||
言語 | eng | |||||||||||||||||
資源タイプ | ||||||||||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
タイプ | journal article | |||||||||||||||||
著者 |
久米, 慶太郎
× 久米, 慶太郎× 天笠, 俊之
WEKO
108908
× 橋本, 哲男
WEKO
130586
× 北川, 博之× Kume, Keitaro |
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抄録 | ||||||||||||||||||
内容記述タイプ | Abstract | |||||||||||||||||
内容記述 | To estimate the functions of mitochondria of diverse eukaryotic nonmodel organisms in which the mitochondrial proteomes are not available, it is necessary to predict the protein sequence features of the mitochondrial proteins computationally. Various prediction methods that are trained using the proteins of model organisms belonging particularly to animals, plants, and fungi exist. However, such methods may not be suitable for predicting the proteins derived from nonmodel organisms because the sequence features of the mitochondrial proteins of diversified nonmodel organisms can differ from those of model organisms that are present only in restricted parts of the tree of eukaryotes. Here, we proposed NommPred, which predicts the mitochondrial proteins of nonmodel organisms that are widely distributed over eukaryotes. We used a gradient boosting machine to develop 2 predictors—one for predicting the proteins of mitochondria and the other for predicting the proteins of mitochondrion-related organelles that are highly reduced mitochondria. The performance of both predictors was found to be better than that of the best method available. | |||||||||||||||||
書誌情報 |
Evolutionary Bioinformatics 巻 14, p. 1-12, 発行日 2018-11 |
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ISSN | ||||||||||||||||||
収録物識別子タイプ | ISSN | |||||||||||||||||
収録物識別子 | 1176-9343 | |||||||||||||||||
PubMed番号 | ||||||||||||||||||
識別子タイプ | PMID | |||||||||||||||||
関連識別子 | 30626996 | |||||||||||||||||
DOI | ||||||||||||||||||
識別子タイプ | DOI | |||||||||||||||||
関連識別子 | 10.1177/1176934318819835 | |||||||||||||||||
権利 | ||||||||||||||||||
権利情報 | © The Author(s) 2018 | |||||||||||||||||
権利 | ||||||||||||||||||
権利情報 | Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). | |||||||||||||||||
著者版フラグ | ||||||||||||||||||
値 | publisher | |||||||||||||||||
出版者 | ||||||||||||||||||
出版者 | SAGE PUBLICATIONS LTD |