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A Case of Primary Combined Squamous Cell Carcinoma with Neuroendocrine (Atypical Carcinoid) Tumor in the Floor of the Mouth
http://hdl.handle.net/2241/00145309
http://hdl.handle.net/2241/001453094fba3622-cff9-4a1c-8345-08ddcf334cd3
名前 / ファイル | ライセンス | アクション |
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CRD_2016-7532805 (5.4 MB)
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Item type | Journal Article(1) | |||||||||
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公開日 | 2017-02-17 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | A Case of Primary Combined Squamous Cell Carcinoma with Neuroendocrine (Atypical Carcinoid) Tumor in the Floor of the Mouth | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||||||
タイプ | journal article | |||||||||
アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
著者 |
山縣, 憲司
× 山縣, 憲司× Terada, Kazuhiro
× 内田, 文彦× 菅野, 直美× Hasegawa, Shogo
× 柳川, 徹× 武川, 寛樹 |
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | The combined squamous cell carcinoma (SCC) with neuroendocrine (atypical carcinoid (AC)) tumor is extremely rare in the head and neck. We present here the first case of SCC with AC arising in the floor of the mouth of 65-year-old man. The tumor is comprised of two components of SCC and AC in the biopsy specimen. Neuroendocrine tumor component was classified as AC from the punctate necrosis and 2–10>/10 HPF. Immunohistochemical staining was HMW-CK/34B (+) and P63 (+) in SCC and synaptophysin (+) and CD56 (+) in AC. The pathological diagnosis of SCC with AC was made from both the morphological and immunological exam. Concurrent chemoradiotherapy was performed with radiotherapy 70.2 Gy and chemotherapy of CDDP and VP-16. Although the treatment effect was complete response both of primary tumor and of neck metastases, the recurrence of the primary tumor was after 6 months. Bilateral modified radical neck dissection and tumor resection of the floor of the mouth with reconstructive surgery of anterior lateral thigh free flap were performed. Although the primary and neck tumor did not recur, the multiple lung metastases and mediastinum lymph node metastases occurred at 6 months after surgery. | |||||||||
言語 | en | |||||||||
書誌情報 |
en : Case Reports in Dentistry 巻 2016, p. 7532805, 発行日 2016 |
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ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 2090-6447 | |||||||||
PubMed番号 | ||||||||||
識別子タイプ | PMID | |||||||||
関連識別子 | 28116178 | |||||||||
DOI | ||||||||||
関連タイプ | isIdenticalTo | |||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.1155/2016/7532805 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | (c) 2016 Kenji Yamagata et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||||||
出版タイプ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Hindawi Publishing Corporation |