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Joint impact of muscle mass and waist circumference on Type 2 Diabetes in Japanese middle‐aged adults : The Circulatory Risk in Communities Study (CIRCS)
http://hdl.handle.net/2241/00160069
http://hdl.handle.net/2241/0016006942671f54-2597-438f-b08f-cffd51255f5b
名前 / ファイル | ライセンス | アクション |
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JDiabetes_13049 (316.2 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2020-05-27 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Joint impact of muscle mass and waist circumference on Type 2 Diabetes in Japanese middle‐aged adults : The Circulatory Risk in Communities Study (CIRCS) | |||||
その他のタイトル | ||||||
その他のタイトル | 肌肉量和腰围对日本中年人2型糖尿病的联合影响 : 循环系统风险的社区研究(CIRCS) | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
山岸, 良匡
× 山岸, 良匡× Yasuoka, Mikako× Muraki, Isao× Imano, Hironori× Jinnouchi, Hiroshige× Kubota, Yasuhiko× Hayama-Terada, Mina× Umesawa, Mitsumasa× Ohira, Tetsuya× Kitamura, Akihiko× Okada, Takeo× Kiyama, Masahiko× Iso, Hiroyasu× CIRCS Investigators |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background Although evidence about skeletal muscle mass loss and type 2 diabetes risk has accumulated, little information is available on the combined effect of skeletal muscle mass and abdominal obesity on type 2 diabetes. We examined whether skeletal muscle mass and abdominal obesity were synergistically associated with the prevalence of type 2 diabetes. Methods Skeletal muscle mass and waist circumference (WC) were measured in 1515 Japanese aged 40 to 69 years. Relative muscle mass was calculated as percentage of total skeletal muscle mass in body weight (SMM%). Type 2 diabetes was identified as fasting serum glucose ≥7.0 mmol/L (126 mg/dL), nonfasting serum glucose ≥11.1 mmol/L (200 mg/dL), glycosylated hemoglobin ≥ 6.5%, and/or diabetes medication use. Results The multivariable-adjusted odds ratio (OR) of prevalent diabetes from the lowest to the third quartile of SMM% compared to the highest quartile gradually increased in both sexes. The association between a high WC and prevalent diabetes was similar. The multivariable-adjusted OR (95% confidence intervals) for the prevalence of type 2 diabetes in the low skeletal muscle mass/high WC group was 3.19 (1.78-5.71) for men and 4.46 (2.09-9.51) for women compared with the high skeletal muscle mass/low WC group. The relative excess risk due to interaction was 2.2 (0.5-3.9) in men and 2.8 (0.2-5.3) in women for an excess burden of type 2 diabetes for low skeletal muscle mass and high WC. Conclusions Low skeletal muscle mass and abdominal obesity were synergistically associated with presence of type 2 diabetes. |
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書誌情報 |
en : Journal of diabetes 巻 12, 号 9, p. 677-685, 発行日 2020-09 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 17530393 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12488308 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 32372543 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1111/1753-0407.13049 | |||||
権利 | ||||||
権利情報 | © 2020 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd. | |||||
権利 | ||||||
権利情報 | This is the peer reviewed version of the following article: Journal of Diabetes 12(9), 677-685 (2020), which has been published in final form at https://doi.org/10.1111/1753-0407.13049. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | WILEY |