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Linalool odor stimulation improves heat stress tolerance and decreases fat accumulation in nematodes
http://hdl.handle.net/2241/00157837
http://hdl.handle.net/2241/00157837f0de5850-c371-4fbc-a673-afe751fb8e38
名前 / ファイル | ライセンス | アクション |
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BBB_83-1 (500.1 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2019-10-03 | |||||
タイトル | ||||||
タイトル | Linalool odor stimulation improves heat stress tolerance and decreases fat accumulation in nematodes | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
坂本, 和一
× 坂本, 和一× Hirano, Naoko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Aromatherapy uses plant essential oils and fragrant ingredients for relaxation, sleep assistance, and improvement of restlessness related to dementia. Certain aromatic substances increase the life span and stress tolerance of nematodes. We investigated effects of exposure to linalool, a linear chain monoterpenic alcohol that is present in the essential oils of many plants, and its optical isomer, l-linalool, in Caenorhabditis elegans. Nematodes were repelled by the odor of both linalool and l-linalool; however, linalool odor stimulation decreased fat accumulation and increased motility after thermal stress. Analysis of a gene-deficient mutant revealed that the DAF-16 insulin-signaling pathway, which is involved in heat stress tolerance, was enhanced by linalool treatment. Linalool stimulation increased the expression of downstream genes such as sod-3 and hsp-12.6 via DAF-16. We conclude that linalool odor induces a repelling behavior in nematodes, improves heat stress tolerance through the DAF-16 signaling pathway, and affects fat accumulation. | |||||
書誌情報 |
Bioscience, biotechnology, and biochemistry 巻 83, 号 1, p. 148-154, 発行日 2018-09 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0916-8451 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10824164 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 30200822 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1080/09168451.2018.1518699 | |||||
権利 | ||||||
権利情報 | This is an Accepted Manuscript of an article published by Taylor & Francis in Bioscience, Biotechnology, and Biochemistry on Volume 83, Issue 1, 2019 available online: http://www.tandfonline.com/10.1080/09168451.2018.1518699. | |||||
著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | TAYLOR & FRANCIS |