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Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of turmeric, is an anti-inflammatory agent. Therefore, it is plausible to hypothesize that curcumin improves arterial compliance. We investigated the effects of curcumin ingestion alone and in combination with aerobic exercise training on arterial compliance in postmenopausal women.\n\nMethods\nA total of 51 postmenopausal women were assigned to 4 groups: placebo, curcumin, exercise and placebo (Ex + placebo), and exercise and curcumin (Ex + curcumin). Curcumin or placebo was ingested orally for 8 weeks. The exercise groups underwent moderate aerobic exercise training for 8 weeks.\n\nResults\nCarotid arterial compliance increased significantly in the curcumin, Ex + placebo, and Ex + curcumin groups, whereas no such changes were observed in the placebo control group. The magnitude of increases in carotid arterial compliance was the greatest in the Ex + curcumin group.\n\nConclusion\nWe concluded that curcumin ingestion improves carotid arterial compliance and that the combination of curcumin and aerobic exercise training was more efficacious in increasing central arterial compliance than either of these treatments alone in postmenopausal women.", "subitem_description_type": "Abstract"}]}, "item_5_publisher_27": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier B.V."}]}, "item_5_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.artres.2012.09.003", "subitem_relation_type_select": "DOI"}}]}, "item_5_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2012 Association for Research into Arterial Structure and Physiology. 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Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women
http://hdl.handle.net/2241/00124289
http://hdl.handle.net/2241/00124289f7a58a4e-b25c-458a-bf06-776e6e243a2e
名前 / ファイル | ライセンス | アクション |
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AR_7-1 (294.3 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2015-04-16 | |||||
タイトル | ||||||
タイトル | Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Akazawa, Nobuhiko
× Akazawa, Nobuhiko× Choi, Youngju× Miyaki, Asako× Tanabe, Yoko× Sugawara, Jun× Ajisaka, Ryuichi× Maeda, Seiji |
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著者別名 |
赤澤, 暢彦
× 赤澤, 暢彦× 鰺坂, 隆一× 前田, 清司 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background Reduction in arterial compliance with aging increases the risk of cardiovascular disease. Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of turmeric, is an anti-inflammatory agent. Therefore, it is plausible to hypothesize that curcumin improves arterial compliance. We investigated the effects of curcumin ingestion alone and in combination with aerobic exercise training on arterial compliance in postmenopausal women. Methods A total of 51 postmenopausal women were assigned to 4 groups: placebo, curcumin, exercise and placebo (Ex + placebo), and exercise and curcumin (Ex + curcumin). Curcumin or placebo was ingested orally for 8 weeks. The exercise groups underwent moderate aerobic exercise training for 8 weeks. Results Carotid arterial compliance increased significantly in the curcumin, Ex + placebo, and Ex + curcumin groups, whereas no such changes were observed in the placebo control group. The magnitude of increases in carotid arterial compliance was the greatest in the Ex + curcumin group. Conclusion We concluded that curcumin ingestion improves carotid arterial compliance and that the combination of curcumin and aerobic exercise training was more efficacious in increasing central arterial compliance than either of these treatments alone in postmenopausal women. |
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書誌情報 |
Artery research 巻 7, 号 1, p. 67-72, 発行日 2013-03 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1872-9312 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12384517 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.artres.2012.09.003 | |||||
権利 | ||||||
権利情報 | © 2012 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. | |||||
権利 | ||||||
権利情報 | NOTICE: this is the author’s version of a work that was accepted for publication in Artery research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Artery research, 7, 1, 2013, DOI:10.1016/j.artres.2012.09.003 | |||||
著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | Elsevier B.V. |