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Age Differences in the Relation Between ACTN3 R577X Polymorphism and Thigh-Muscle Cross-Sectional Area in Women
http://hdl.handle.net/2241/114062
http://hdl.handle.net/2241/1140620fbde47c-c7ed-4149-bdbb-57dde821adb8
名前 / ファイル | ライセンス | アクション |
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GTMB_15-9.pdf (306.1 kB)
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Item type | Journal Article(1) | |||||
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公開日 | 2011-10-05 | |||||
タイトル | ||||||
タイトル | Age Differences in the Relation Between ACTN3 R577X Polymorphism and Thigh-Muscle Cross-Sectional Area in Women | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Zempo, Hirofumi
× Zempo, Hirofumi× Tanabe, Kai× Murakami, Haruka× Iemitsu, Motoyuki× Maeda, Seiji× Kuno, Shinya |
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著者別名 |
前田, 清司
× 前田, 清司× 久野, 譜也 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The relation between ACTN3 R577X polymorphism and muscle mass in women has been reported, but its relation to age remains unclear. We investigated the relationship between ACTN3 R577X polymorphism and muscle mass in both middle-aged and elderly women. Two age groups (middle-aged and older) were formed among 162 healthy, nontraining Japanese women (mean±SE, 58.6±0.8 year). Their midthigh-muscle cross-sectional area (CSA) was assessed using magnetic resonance imaging, revealing no difference in thigh-muscle CSA among ACTN3 R577X genotypes in the middle-aged group (XX, 87.3±2.5 cm2; RR&RX, 86.1±1.7 cm2, p=0.7). In contrast, the XX genotype in the older group had a smaller thigh-muscle CSA adjusted to body weight than the RR&RX genotypes (XX, 67.8±2.0 cm2; RR&RX, 72.5±1.2 cm2, p<0.05). The present study showed an association between ACTN3 R577X polymorphism and smaller thigh-muscle CSA in a group of elderly women but not in a group of middle-aged women. | |||||
書誌情報 |
Genetic testing and molecular biomarkers 巻 15, 号 9, p. 639-643, 発行日 2011-09 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1945-0265 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA1238373X | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 21491997 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1089/gtmb.2011.0005 | |||||
著者版フラグ | ||||||
値 | author | |||||
出版者 | ||||||
出版者 | Mary Ann Liebert | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2241/114062 | |||||
識別子タイプ | HDL |